Chemical name: Exemestane
Product Category: Pharmaceutical raw materials and intermediates
Product content: ≥ 99%
CAS Number: 107868-30-4
Molecular formula: C20H24O2
Packing specifications: 25kg / barrel
Molecular weight: 296.4
Appearance: White or Almost White Crystalline Powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Assay(by HPLC): 98.0-101.2%min
Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds.
Aromasin (Exemestane) is one of those weird compounds that nobody really knows what to do with. It's a third generation Aromatase Inhibitor (AI) just like Arimidex () and Femera ().
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
1. Aromasin is one of the most powerful estrogen suppressing compounds.
2. Aromasin is one of the best compounds to lower the aromatizing effect of steroids.
3. Aromasin is available for body builders taking anabolic steroids.
4. Aromasin is also known as .
5. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.
6. Aromasin is also a kind of .antineoplastic (hormonal) raw materials.
1. exemestane is an oral steroidal aromatase inhibitor that is used in er-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
2. it acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition."
3. by being structurally similar to enzyme targets, exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Exemestane is usually not used in women of childbearing age.
The recommended dose of AROMASIN in early and advanced breast cancer is one 25 mg tablet once daily after a meal.
adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to AROMASIN for completion of a total of five consecutive years of adjuvant hormonal therapy.
the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.