Mk-1775 CAS:955365-80-7 Sarms Powder
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keywoeds: Mk-1775
1.Product Introduction
Product Name: MK-1775
Alias: MK1775, MK 1775
CAS: 955365-80-7
Molecular Formula: C27H32N8O2
Molecular Weight: 500.59538
Assay: 99.50%
Grade: Pharmaceutical Grade
Appearance: Yellow powder
Storage: 0-5 ℃
2. Product description:
MK-1775, also known as adavosertib, AZD-1775, is a WEE1 inhibitor, is also a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents.
3. MK-1775 COA :
| Product name | MK-1775 | ||
| CAS No. | 955365-80-7 | Outer Packing | 50g/bag |
| Production date | 2018.07.07 | Shelf life | 2020.07.06 |
| Standard adopted | In-house Quality Standard | ||
| Items of analysis | Specification | Results | |
| Visual Description | Yellow solid | Yellow solid | |
| Identification 1H NMR | Confirms to structure | Confirms | |
| Purity | ≥ 99% | 99.3% | |
| Conclusion | Qualified | ||
4. Order Process:
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MK1775 | 955365-80-7 |
