1.Product Introduction
Welcome to contact Morgan for more details.Whatsapp:+8617725670492, email:liuxf@yccreate.com.
2.Specifications:
| Product Name | SR9011 |
| Alias | 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide |
| CAS NO | 1379686-30-2 |
| Appearance | White powder |
| MF | C20H24ClN3O4S |
| MW | 479.04 |
| Purity | 99%min |
| Origin | China |
| Export market | Global |
| Grade | Pharmaceutical grade |
| Supply capacity | Mass in stock |
| Usage | For obesity, diabetes, dyslipidemia and cardiovascular disease. |
| Packing | Well disguised package to pass the customs |
| Payment | T/T, Western Union,Moneygram and Bitcoin. |
| Shipping | EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc |
| Leading time | Within 24 hours after payment. |
| Delivery time | 3-7 work days |
| 99% passing rate & 100% free resend policy | |
3.Applications:
SR9009 and SR9011 are attractive as performance-enhancing substances due to their REV-ERB agonist effects and thus circadian rhythm modulation activity.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
SR9011 Not Just a "Diet" Pill
There's no way to sugarcoat it-though many have tried-maintaining a healthy weight can be difficult. Because it's hard, many have tried "miracle" weight-loss pills and other quick fixes for something that ultimately requires a lifestyle change. Many over-the-counter diet and weigh-loss pills are unregulated and may contain dangerous ingredients. SR9011, however, isn't like appetite suppressants, laxatives, or "fat blockers." And you won't find SR9011 in the ingredient lists of protein powders or exercise supplements.
The difference between SR9009 and other diet pills is in its chemistry. SR9011 is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.
SR9011 is one of a pair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erbα,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erbα, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.
4.prodection details
COA
| Item | Specification | Result |
| Appearance | An odorless, almost white or white powder | pass |
| Identificaton | The retention time of the major peak is confirm to the RS | pass |
| Loss on Drying | Not more than 0.5% | 0.33% |
| Assay(HPLC) | Not less than 99.0% | 99.59% |
| Ignition residue | Not more than 0.1% | pass |
| Heavy metal | Not more than 20 ppm | pass |
5. Packaging & Delivery
1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products, Finished products, OEM service.
We can also assist with formulations, blends and custom packing. MOVERS is your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2. WHEN will my order ship?
Products in stock usually ship within 24-48 hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.
3. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.
4. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices.
