Hydroxyprogesterone CAS 68-96-2

17α-Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid).

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Estrogen Hormone Powder 17alpha-Hydroxyprogesterone CAS 68-96-2 

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17α-Hydroxyprogesterone Basic Info

Product NameHydroxyprogesterone
Alias17alpha-Hydroxyprogesterone, 17-OHP
PHYSICAL STATEwhite crystalline powder
Usagea metabolite of Progesterone
StorageStore in cool and dry places, keep away from strong light
Package methodshundreds of disgusied pacakges
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17α-Hydroxyprogesterone Descrption

17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesisof othersteroid hormones, including the corticosteroids and the androgens and the estrogens.  17-Hydroxyprogesterone is an important intermediate for the synthesis of steroid corticosteroids and steroid progesterone drugs. Betamethasone, hydrocortisone, progesterone hexanoate, cortisone acetate and chlorgesterone can be synthesized from it.

17α-Hydroxyprogesterone Application

17a-Hydroxyprogesterone caproate CAS 630-56-8 is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin).

Hydroxyprogesterone is a man-made form of a female hormone (progestin). Hydroxyprogesterone is not known how it works to prevent preterm labor. 17a-Hydroxyprogesterone is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). Hydroxyprogesterone is also not intended to stop active preterm labor. 17α-OHP increases in the third trimester of pregnancy primarily due to fetal adrenal production. This steroid is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. 

17α-Hydroxyprogesterone COA

  • Standard:USP31
    DescriptionWhite or almost white crystalline powder, odorlessConforms
    Solubilityinsoluble in water, solube in ether, slightly soluble in benzeneConforms
    Specific Optical Rotation+58°---+64° (1% chloroform Solution)60.3°
    Melting Pointabout 120 -124 ºC123ºC
    Free N-Caproic Acid≤0.58%0.20%
    Ordinary Impurities≤2.0%conforms
    Residual SolventsMethanol ≤ 3000PPM1280PPM
    Dichloromethane ≤ 600PPM80PPM
    ConclusionConforms to USP31


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