Estrone CAS: 53-16-7 Raw Powder
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Keywords: Estrone; Oestrone; CAS: 53-16-7;
1. Product Introduction
Product name: Estrone
2. Product description:
Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is an odorless, solid crystalline powder, white in color with a melting point of 254.5 °C and a specific gravity of 1.23.Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the threehormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily duringpregnancy.
3. Estrone COA
| Items | Standards | Results |
| Appearance | White or off-white powder | Complies |
| Identification | By IR | Complies |
| By HPLC | Complies | |
| Solubility | Soluble in dichloromethane | Complies |
| Melting Point | 160ºC~164ºC | 162.1ºC~163.6ºC |
| Loss on Drying | ≤ 0.50% | 0.31% |
| Heavy Metals | ≤ 10ppm | Complies |
| Residue on Ignition | ≤ 0.10% | 0.09% |
| Isomer | ≤ 0.50% | 0.10% |
| Related Substances | Maximum single impurity: ≤0.50% | 0.13% |
| Total impurities: ≤1.00% | 0.63% | |
| Assay (HPLC) | 98.0%~102.0% | 99.52% |
| Reference Standard | In-house Standard | |
| Conclusion | The product complied to In-house standard. | |
| Storage | Preserve in tight,light-resistant containers in a cool place | |
4. Estrone Applications:
Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily duringpregnancy.
Estrone is known to be a carcinogen for human females as well as cause breast tenderness or pain, nausea, headache, hypertension, and leg cramps. In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile dysfunction.Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
5. Related Products:
| Estradiol | Estrone | Durabolin |
| Estradiol valerate | Estriol | Hydrocortisone |
| Estradiol benzoate | Nylestriol | Hydrocortisone acetate |
| Estradiol cypionate | Diethylstilbestrol | Meprednisone |
| Estradiol enantate | HEXESTROL | Prednisone acetate |
| Ethynyl estradiol | Progesterone | Bentelan |
| Algestone acetophenide | Medroxyprogesterone acetate | Betamethasone |
| Ethisterone | Norethindrone | Clobetasol propionate |
| 19-Norethindrone acetate | Mifepristone | Halobetasol propionate |
| Norethisterone Enanthate | Methyldienedione | Deflazacort |
| Ethynodiol diacetate | Eplerenone | Tazarotene |
| Pregnenolone acetate | Levonorgestrel | Ecdysone |
| Lynestrenol | Allylestrenol | Desloratadine |
| Chlormadinone acetate | Dienogestrel | Prednisolone phosphate sodium |
| Cyproterone acetate | Drospirenone | Fluorometholone Acetate |
| Megestrol acetate | Pregnenolone | Dexamethasone Acetate |
| Melengestrol acetate | Mometasone furoate | Dexamethasone Sodium Phosphate |
| Betamethasone acetate | Beclomethasone dipropionate | Dexamethasone palmitate |
| Betamethasone Dipropionate | Betamethasone 17-valerate | Fluocinolone acetonide |
6. Order Process:
