Estriol CAS.50-27-1

Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor.

Product Details

Estrogen Hormone Estriol CAS50-27-1 For Female Health

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Estriol Quick Details

Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor.


Product Name

Estriol

CAS

50-27-1

MF

C18H24O3

Molecular Weight

288.39

EINECS

200-022-2

ensity

1.255 g/cm3

Melting Point

280-282 °C(lit.)

Boiling Point

469 °C at 760 mmHg

lash Point

220.8 °C

Appearance

White crystalline powder

Assay

99%

Storage

as per relevent regulations

Usage

pharmaceutical intermediates


Estriol Application:

1) Used for treating cervicitis, especially suitable for treating menopausal syndrome and senile vaginitis.
2) Used as the adjuvant drug for middle-term labor induction and artificial abortion.
3) Used for treating prostatic hypertrophy and prostate cancer.
4) In addition, it still has a rapid role in increasing the peripheral leukocytes.
5) It has efficacy in treating leukopenia caused by chemotherapy or radiotherapy as well as reducing the vascular permeability and fragility and can be used for the treatment of various kinds of hemorrhage.
6) It also has quick hemostasis effect on menorrhagia, hysterectomy or tonsillectomy.


Estriol(3)


How to Dose Estriol

The typical oral dose used in Western Europe is 2 to 5 mg daily, but because much of it is "dumped" by

the liver immediately, this may only ultimately amount to ½ to 1 mg of estriol actually getting into the body.

Many clinicians use an estriol cream that delivers 2 to 5 mg. When made as a cream, the pharmacist

should indicate on the container how much cream it takes to provide the 2 to 5 mg of estriol.

When you deliver estriol to your body via a cream, it is delivered in a much steadier fashion, whereas given orally it is subject to all the variables of how the digestive system and the liver are working from hour to

hour.


An estriol cream that delivers 0.5 mg, used every other day, has been shown to be very effective for treating vaginal atrophy and urinary tract infections. Published studies show that 0.5 mg estriol delivered every other day for 2 weeks, is adequate for most women, and this is how estriol is used by most women in

Europe.


The reason that estriol is used only every other day is because it doesn't clear from the body as fast as the other estrogens and therefore one dose will last for two days. Using it every day can result in excessively high levels. Although estriol does not absorb through the skin as rapidly as estradiol or estrone, studies have shown that topical delivery of estriol is about twenty times more efficient than oral delivery.


Estriol Specification:

Items

Specification

Results

Appearance

White to practically white, odorless, crystalline powder.

white crystalline powder, odorless

Identification

A:IR B:UV

Conforms

Melting point

About280ºC

281.5ºC

Solubility

Insoluble in water; sparingly soluble in alcohol; soluble in acetone, n ether, and in vegetable oils

Conforms

Completeness of solution

The solution is clear and free from undissolved solid.

Conforms

Loss on drying

≤0.5%

0.26%

Specific optical rotation

+54°~ +62°

+57.07°

Total impurities

≤2.0%

Conforms

Residue on ignition

≤0.1%

0.06%

Assay

≥98%



Order Process

Make an order:

Please make clear the quantity

Mini Order:

10g

Quote:

Prices confirm

Payment ways:

T/T, Western Union, Money Gram and Bitcoin

Delivery ways:

All Express Modes(EMS, DHL, TNT, FedEx, UPS,etc.)

Shipping address:

Provide your Valid and Correct destination address info(if possible with post code, phone number).

Packing:

Select best ways according to quantity and safety degree(Super discreet, professional and experienced)

Lead time:

Within 24 hours upon receipt of payment

Package pictures:

Photos of parcel would be offered to tell apart the items

Tracking number:

Offered once it is released

Shipping time:

5-7 working days (Door-to-Door)

After-sale service:

24/7 Online for any problems


Rules of Shipping

All our products can be shipped worldwide and to assure the loyalty and discretion of our client we respect the following rules:

We never use in our shipments the name of our company or any content implying pharmacy .

We use designed discreet packing methods according to different countries and quantity, universal and secure.

We practice constant changes in the types of packaging we use, thus achieving a maximum success in delivery procedure.

We use small packages to raise a lower level of susceptibility.

We ship the products in original cardboard boxes to assure a healthy and ecological medium.


Estriol(4)


Order not received or delays in arrival

Some orders may not arrive or be delayed mainly due to custom seizure or they could be lost in the mail. In cases when the package is seized at customs, please send us the seizure letter from customs or FDA at and we will undertake the necessary measures.

Our policy is to reship the products only once.In order to follow and track your package shipping process, you may check the "Order History" link for the estimated date or dates of delivery.


FREQUENTLY ASKED QUESTIONS

QUESTIONS

ANSWERS

Q1: You are manufacturer or trader?

Combined, pls contact us for specicfic product consulting.

Q2: Do you provide free sample?

Yes, but please bear shippping cost at your side. Ship fee will be deducted from future bulk order

Q3: Can you give a discount?

Surely, it depends on your quantity

Q4: How will you dispatch product?

For small quantity order, FedEx,DHL, TNT, USP, EMS, by air.

For commercial qty, by sea is alternative.

Q5: How i pay by credit card?

Credit cart paying is avaliable by western union and money gram


SERVICE

Click right contatc supplier, or contact with followed information, you will be replied within 24 hours.

Your questions will be replied timely and positively solved during order.


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COMPANY INFORMATION

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Our mission is contuniously keeping on satisfyting quality and reduce cost of product, and share the fruits of benefits with our customers.


We aim to achieve a strong presence in providing fine chemicals, especially in anti-cancer, peptide, herbal plant and achieving well recognition domestically and internationally.


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