Estradiol Enantate

Estradiol enantate , also spelled estradiol enanthate and sold under the brand names Perlutal and Topasel among others, is an estrogen medication which is used in hormonal birth control for women.Any needs contact :whatsapp:+8613378646535

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        Estradiol enanthate raw powder female hormone CAS:4956-37-0

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Product name: Estradiol enanthate

Synonyms: Oestradiol 17-heptanoate/B-estradiol 17-enanthate

Estradiol enantate

Purity: 99%

CAS No.: 4956-37-0

ECNECS No.: 225-599-8

MF: C25H36O3

MW: 384.5515

Density: 1.11 g/cm 3

Melting Point: 94-96o C

Boiling Point: 509.5o C at 760 mmHg

Refractive Index: 1.559

Flash Point: 197.1o C

Appearance: White crystalline powder

Grade: Pharmaceutical Grade

pack:as requirments

Packing: 1kg/aluminum foil bag


Estradiol enantate, sold beneath the brand names Perlutal and Topasel amongst other folks, is an estrogen medication which is made use of in hormonal birth handle. It really is formulated in mixture with dihydroxyprogesterone acetophenide (DHPA; algestone acetophenide), a progestin, and is made use of as a combined injectable contraceptive. Estradiol enantate just isn't obtainable alone. The medication is provided by injection into muscle when a month.

Side effects of estradiol enantate consist of breast tenderness, breast enlargement, nausea, headache, and fluid retention. The drug is really a synthetic estrogen and therefore is an agonist from the estrogen receptor (ER), the biological target of estrogens like estradiol. Estradiol enantate is an estrogen ester as well as a long-lasting prodrug of estradiol in the physique. For this reason, it is viewed as to become a all-natural and bioidentical kind of estrogen.

Estradiol enantate was 1st described by 1954, and was 1st studied in mixture with DHPA as a combined injectable contraceptive in 1964. The mixture was introduced for clinical use by the mid-1970s. Estradiol enantate just isn't accessible as a standalone medication (i.e., by itself with out DHPA). The mixture is readily available in Latin America and Hong Kong, and was also previously marketed in Spain and Portugal.


Female reproduction:In the female, estradiol acts as a hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary.

During the menstrual cycle, estradiol produced by the growing follicle triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to the luteinizing hormone surge, inducing ovulation. In the luteal phase, estradiol, in conjunction with progesterone, prepares the endometrium for implantation. During pregnancy, estradiol increases due to placental production. In baboons, blocking of estrogen production leads to pregnancy loss, suggesting estradiol has a role in the maintenance of pregnancy. Research is investigating the role of estrogens in the process of initiation of labor. Actions of estradiol are required before the exposure of progesterone in the luteal phase.


Hormones and Regulation of Endocrine Function of Drug, Nutritional Therapeutics, Antibiotic and Antimicrobial Agents, Antiparasitic, Original Drug Resistant Microbes, Immune System Drugs, Specialist Drugs, Drug Detoxification, Diagnostic Agents, Blood System Agents, Visceral System Medication, Central Nervous System Agents, Cardiovascular Agents, Urinary System Agents, Respiratory System Agents.

A chemical deritative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.

How does it to work in our body?

Women's menstrual cycle involves several predictable changes in hormone levels, of which Estradiol Benzoateis one of them. Participate in the ovulation process, prepare the endometrial implant, the egg should be fertilized. Some tests on baboons and other primates show that his hormones also play a sustained role in maintaining pregnancy and contribute to the duration of pregnancy.

As a sex hormone, Estradiol Benzoatealso triggers many of the development of adolescent reproductive systems. It exists throughout the reproductive year and falls during and after menopause. This decline is the result of many symptoms of menopausal symptoms, such as hot flashes and night sweats, vaginal dryness and bone loss that may lead to osteoporosis.

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