Pharmaceutical Raw Material Tinidazole CAS 19387-91-8 For Antibacterial
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Tinidazole Basic Info
|PHYSICAL STATE||white crystalline powder|
|Usage||Widely used in the prevention and treatment of infection of anaerobic bacteria and protozoan diseases|
|Storage||Store in cool and dry places, keep away from strong light|
|Package methods||hundreds of disgusied pacakges|
|After-sales service||Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.|
|Shipping method||FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.|
|Delivery time||delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking|
|Payment Methods||Western union, money gram, bitcoin and bank transfer|
Tinidazole is a synthesized imidazole derivative used in antiprotozoal treatment with antiamebic and antibacterial properties.
Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections. It was developed in 1972. A derivative of 2-methylimidazole, it is a prominent member of the nitroimidazole antibiotics
Tinidazole is a nitroimidazole similar to metronidazole and is activated intracellularly by bacterial or parasitic enzymes to a radical anion, which damages large protein molecules and DNA. Tinidazole was approved for use in the United States in 2004 and current indications are for treatment of trichomoniasis, giardiasis, amebiasis and bacterial vaginosis.
A large body of clinical data exists to support use of tinidazole for infections from amoebae, giardia and trichomonas, just like metronidazole. Tinidazole may be a therapeutic alternative in the setting of metronidazole tolerance.
Tinidazole may also be used to treat a variety of other bacterial infections (e.g., as part of combination therapy for Helicobacter pylori eradication protocols).
How to use Tinidazole
Tinidazole is available in tablets of 250 and 500 mg and the dose varies by indication, being 2 grams as a single oral dose in adults with trichomoniasis and giardiasis, and for 3 to 5 days for moderate or severe forms of amebiasis. Oral tinidazole is generally well tolerated if being used generally for only 1 to 5 days. Side effects can include metallic or bitter taste, fatigue, dizziness, headache, dyspepsia, nausea, and a disulfiram-like response to alcohol. Rare, but potential serious adverse events include allergic reactions, anaphylaxis and toxic megacolon.
|Appearance||White or pale yellow crystalline powder||White crystalline powder|
|Solubility||Practically insoluble in water, soluble in acetone and in methylene chloride, sparingly soluble in methanol||Conforms|
|Identification||The IR spectrum corresponds to Tinidazole reference standard||Conforms|
|Appearance of solution||5.0%(g/ml)solution in acetone should be clear and not more intensely colored than reference solution Y5||Conforms|
|Related substances(TLC)||Impurity-A:NMT 0.5%||0.5%|
|Any other unspecified impurity: NMT 0.5%||0.5%|
|At most one impurity more than 0.2%||Conforms|
|Residual solvents(GC)||Ethanol: NMT 1000 ppm||190 ppm|
|O-xylene: NMT 195.3 ppm||90 ppm|
|Loss on drying||NMT 0.5%||0.08%|
|Sulphated ash||NMT 0.1%||0.04%|
|Heavy metals||NMT 20 ppm||20 ppm|
|Assay||NLT 98.0% & NMT 101.0% (dried substance)||99.4%|
According to customer's requiement
Prompt shipment after receipt of your order confirmation
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
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5. High customs clearance pass rate.
Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.
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