Pharmaceutical Raw Material Terbinafine HCL CAS 78628-80-5 For Antifungal
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Terbinafine HCL Basic Info
| Product Name | Terbinafine Hydrochloride |
| Alias | lamosil, Terbinafine HCL, Lamisil |
| CAS | 78628-80-5 |
| MF | C21H26ClN |
| MW | 327.89 |
| EINECS | 616-640-4 |
| Assay | 99.0% |
| PHYSICAL STATE | white crystalline powder |
| Usage | a synthetic allylamine antifungal |
| Storage | Store in cool and dry places, keep away from strong light |
| Package methods | hundreds of disgusied pacakges |
| After-sales service | Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible. |
| Shipping method | FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way. |
| Delivery time | delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking |
| Payment Methods | Western union, money gram, bitcoin and bank transfer |
Terbinafine HCL Descrption
Terbinafine HCL is suitable for treatment of candidiasis skin, such as tinea manuum, tinea, tinea, ringworm of the body, tinea versicolor, it is also the best medicine for the treatment of onychomycosis.
Terbinafine hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.
Terbinafine HCL Application
Terbinafine is mainly effective on the dermatophytes group of fungi. As a 1% cream or powder it is used for superficial skin infections such as jock itch (Tinea cruris), athlete's foot (Tinea pedis) and other types of ringworm (Tinea corporis).
Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.
Terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.
Terbinafine may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.
Terbinafine HCL COA
Product name | Terbinafine hydrochloride | ||
CAS No. | 78628-80-5 | Outer Packing | 25KG |
Production date | 2018.06.24 | Shelf life | 2020.06.23 |
Standard adopted | EP8.0 | ||
Items of analysis | Specification | Results | |
Description | White or almost white powder | almost white powder | |
Solubility | very slightly or slightly soluble in water, freely soluble in anhydrous ethanol and in methanol, slightly soluble in acetone | Complies | |
Identification | Infrared absorption spectrophotometry.Comparison: terbinafine hydrochloride CRS | Complies | |
Impurity B | ≤0.15% | Complies | |
unspecified impurities | each Impurity not more than 0.1% | Complies | |
Sum of impurity | not more than 0.3% | Complies | |
Loss on drying | ≤0.5% | 0.14% | |
Sulfated ash | ≤0.1% | 0.08% | |
ethyl acetate | ≤0.5% | Complies | |
dichloromethane | ≤0.06% | Complies | |
isopropanol | ≤0.5% | Complies | |
Assay | 99.0%-101.0% | 99.78% | |
Conclusion | Qualified | ||
FAQ
Q1: Are you a manufacturer ?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: What`s your delivery
A: We send goods in 3 working day after receiving your payment by DHL, FEDEX, TNT, EMS, AIR OR SEA as you request, usually you can find shipping details in 3 to 5 working days after your payment.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
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Q7: Do you provide free sample?
A: We can provide free sample of some chemicals and you just need you to cover the delivery cost.
Shipping & Delivery
1.Packages are generally dispatched within approximately 2 days after receipt of payment.
2.After the each shipping we will provide you with:
1) a link & tracking number to track your package online.
2) the few pictures with your order & details.
3.About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.
4.We confirm 99% clearance,100% resending.
5.Is it the best & safest shipping for all our repeat customers!
Packing Details
Discreet packing ways as your requirement, 100% go through.
Storage
Store in cool and dry area and keep away from direct sunlight.oC
Shelf life
2 years, keep in formal storage condition.
MOQ
We accept any Qty you require, grams to kilograms.
Samples Available, Contact now!
Order info
Payment Methods:West Union,Moeny Gram, Bitcoin and Bank Transfer.
Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
Shipment Time:Within 12 hours after confirmation of your payment
Other Service:Safe shipment,high purity and best price for you.
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