Temozolomide CAS 85622-93-1

Temozolomide is an antitumor, antiangiogenic compound that has been shown to work by alkylating DNA, typically through addition of a methyl group to guanine in genomic DNA.

Product Details


High Quality Temozolomide CAS 85622-93-1 For Anti-Cancer



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Temozolomid Quick Details


Product NameTemozolomid
CAS85622-93-1
MFC6H6N6O2
MW194.15
EINECS630-358-9
Assay99.0%
PHYSICAL STATEwhite crystalline powder
UsageAntitumor Drug
StorageStore in cool and dry places, keep away from strong light
Package methodshundreds of disgusied pacakges
After-sales serviceWarm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
Shipping methodFedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.
Delivery timedelivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking
Payment MethodsWestern union, money gram, bitcoin and bank transfer


Temozolomid Descrption


Temozolomide is the first orally effective imidazotetrazine antitumor drug. It belongs to the second generation of alkylating agent with antitumor activity. Temozolomide does not require intrahepatic metabolic activation after oral administration. Temozolomide is characterized by easy permeability through the blood-brain barrier and tolerance.


Temozolomide Application


The effect of temozolomide in the treatment of recurrent glioblastoma multiforme has been confirmed to be safe and effective in clinical trials. more patients in the temozolomide group had improved quality of life or remained stable. The main adverse effects of temozolomide were transient and non-accumulative myelosuppression, which was predictable and easy to handle, with an incidence of 24% in the trial. 


Temozolomide has a significant effect on gliomas, especially on the most common pleomorphic glioblastoma, both in tumor response rate and in patient survival and tolerability. More importantly, the quality of life of patients is significantly better than the existing standard drug procarbazine, making the treatment of such tumors a welcome step. 


The effect of temozolomide on the first-line treatment of progressive metastatic melanoma has also been affirmed in clinical trials, and applications have been filed in Europe, the United States and other countries.


Temozolomide COA



Test items


Requirements

Results


Description


A White or off-white crystalline powder; odorless; tasted bitter.

Complies


Solubility


Slightly soluble in water, very slightly soluble in dehydrated alcohol, soluble in DMF and very soluble DMSO.

Complies


Identification




A. IR


A: Conform to reference standard

Conforms


B. Chemical Property


B: Dissolve 0.1g the sample with 10ml water, add 5ml dinitro-phenyl-hydrazine, should have marron precipitate.

Positive


C. HPLC


C: The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation

Conforms


Loss on drying


≤ 1.0%.

0.21%


Residue on ignition


≤ 0.1%.

0.07%


Heavy metals


≤ 0.002%.

Complies


Chloride


≤ 0.002%.

Complies


Impurities by HPLC
Any impurity(Max)
Total impurities



≤ 0.1%.
≤ 0.3%.


0.042%
0.08%


Residual solvents
Ethyl acetate
Alcohol
DMSO



≤ 0.5%.
≤ 0.5%.
≤ 0.5%.


Complies
Complies
Complies


Assay (HPLC)


98.5%~102.0%

99.80%


Temozolomid raw


Our Commitment:


1. Quality assurance

With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market to meet the requirements of customers, many customers use our products, we believe that the product is very good. Whether it is a powder, or liquid, yes, we all know, our liquid better.


2. Safe transportation

Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 3-5 to your product.


3. The product diversity

Our products are powders and liquids, yes, brothers, the effect of the liquid is very good, but many people do not use liquid, so you are very lucky, you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter. We absolutely guarantee that you can very safely use our products


4. High quality service

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.


Packaging Details:


1. 1kg Aluminum Foil Bag.

2. Standard packed In fiber-drums with two-plastic bags inside.
Wight: Net weight 25kg/drum; gross weight 28kg/drum
Drum Size & Volume: I.D.37cm x H51cm, 0.070cubic meter/ drum

3. As customer's requested.



Payment & Shipping Details:


Delivery MethodExpress (DHL, FedEx, EMS)By AirBy Sea
Shipping QuantityUnder 100kgOver 100kgOver 500kg
Delivery Time3-5 days5-7 days20-30 days
CharacteristicDoor to DoorAirport to AirportSea Port to Sea Port



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