SERM Raloxifene hydrochloride CAS 82640-04-8 For Breast Cancer
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Raloxifene hydrochloride Quick Details
|Product Name||Raloxifene hydrochloride|
|Alias||Raloxifene HCl; KEOXIFENE; AKOS 92138|
|PHYSICAL STATE||white to light yellow powder|
|Usage||Raloxifene Hydrochloride is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM)|
|Storage||stored in cool, dry and ventilated places, kept far from fire.|
|Package methods||foil bag or drum or as your mind|
|After-sales service||Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.|
|Shipping method||FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.|
|Delivery time||delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking|
|Payment Methods||Western union, money gram, bitcoin and bank transfer|
Raloxifene hydrochloride Descrption
Raloxifene Hydrochloride is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of Raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (Agonism) and and the blockade of estrogenic pathways in other tissues (Antagonism). Raloxifene Hydrochloride has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast.
Raloxifene hydrochloride Application
Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowingbone loss helps to reduce the risk of fractures. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.This medication is not recommended for use in women before menopause.
Raloxifene is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.
Raloxifene hydrochloride prevents and treats osteoporosis by mimicking the effects of estrogen (a female hormone produced by the body) to increase the density (thickness) of bone.
Raloxifene hydrochloride decreases the risk of developing invasive breast cancer by blocking the effects of estrogen on breast tissue. This may stop the development of tumors that need estrogen to grow.
Raloxifene hydrochloride Specification
|Items of analysis||Specification||Results|
|Solubility||Soluble in 10% sodium hydroxide solution. Slightly Soluble in methanol. Insoluble in water||Conform|
|Identifcation||Infrared Absorption / Chloride||Conform|
|Loss on drying||≤0.5%||0.2%|
|Residue on ignition||≤0.1%||0.050%|
|Raloxifene ImpurityⅠ||≤0.2%||0. 1%|
|Any unspecified individual impurity Ⅱ||≤0.10%||Max. 0.08%|
|Conculsion||The results conform to USP34 Standard|
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