Pregabalin CAS: 148553-50-8
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Keywords: Pregabalin; Lyrica; CAS: 148553-50-8
1. Product Introduction
Product Name:Pregabalin,Lyrica
2. Product description:
Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults.It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in the European Union.It was designed as a more potent successor to gabapentin.
Recent studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgiaand spinal cord injury. In June 2007, pregabalin became the first medication approved by the U.S. Food and Drug Administration specifically for the treatment of fibromyalgia.
3. Pregabalin COA
| ITEMS | STANDARDS | RESULTS |
| Appearance | A white to off white powder | White powder |
| Identification | A. Meets the requirement | Complies |
| B. IR: similar to Reference Substance | Complies | |
| Loss on drying | ≤0.5% | 0.21% |
| Specific Rotation | +10.0°~+13.0° | +10.8° |
| Related Substances | Any single impurity ≤0.1% Total impurity ≤0.8% | 0.05% 0.10% |
| Purity By HPLC R-isomer | ≤0.15% | 0.10 |
| Residue on ignition | ≤0.1% | 0.05% |
| Residual solvents | Isopropyl alcohol ≤5000ppm Ethyl Acetate ≤5000ppm | 150ppm 250ppm |
| Heavy metals | ≤10ppm | Complies |
| Chlorides | ≤0.05% | Complies |
| Assay | 98%~102.0% | 99.8% |
| Conclusion | Analyse according to Factory Standard , Conform | |
4. Pregabalin Applications:
Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
Pregabalin,the main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Pregabalin can also be used to treat pain and anxiety.
5. Related Products:
Glucocorticoid Steroid Powder | |
Product Name | CAS NO. |
Dexamethasone | CAS:20-02-2 |
Dexamethasone Sodium Phosphate | CAS:55203-24-2 |
Beclometasone | CAS:5534-09-8 |
Cortisone | CAS:53-06-5 |
Hydrocortisone | CAS:50-03-3 |
Prednisone Acetate | CAS:125-10-0 |
Fluticasone | CAS:948566-12-9 |
mometasone furoate | CAS:83919-23-7 |
Triamcinolone | CAS:76-25-5 |
Beclometasone Dipropionate | CAS:5534-09-8 |
6. Order Process:
7. The quality control process:
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
