1.Product Introduction
Welcome to contact Morgan for more details.Whatsapp:+8617725670492, email:liuxf@yccreate.com.
2.Specifications:
Product name: Pramipexole
Purity:99%
CAS: 104632-26-0
Molecular formula: C10H17N3S
Molecular weight: 247.788
Appearance: white powder
Synonyms: Pramipexol; (-)-Pramipexole; 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-; Mirapexin; Oprymea; Pramipexol [Spanish]; Pramipexole Teva; Pramipexolum; Pramipexolum [Latin]; SUD919CL2Y; Sifrol; U-98528E; UNII-83619PEU5T; (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole; 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (S)-; (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole
3.Applications:
Functions: Pramipexole dihydrochloride is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) andrestless legs syndrome (RLS). It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.
4.prodection details
Test Items | Standard | Test Results |
Character | Off-white to White Crystalline powder | Off-White Crystalline powder |
Solubility | Soluble in Water and Methanol, slightly soluble in Ethanol (96%), Almost insoluble in Dichloromethane | Complies
|
Identification | (1)Specific Rotation -67~-69.5°(on anhydrate basis) (2)IR: Meets the requirement. (3) Optical purity Test (4)Chloride Reaction | -68.8
Complies Complies Complies |
Clarity | Clear, not deeper than Y6. | Complies |
PH | 2.8~3.4 | 3.15 |
Related Substances | Impurity A≤0.15% Impurity B≤0.15% Impurity C≤0.15% Unknown single impurity≤0.1% Total Impurity≤0.5% | Not detected 0.04% Not detected 0.05% 0.16% |
Impurity D | Impurity D≤0. 5% | 0.1% |
Water | 4.5%~6.5% | 4.9% |
Heavy metals | ≤10ppm | Complies |
Sulfate Ash | ≤0.1% | 0.05% |
Assay (on anhydrate basis) | 99.0%~101.0% | 99.8% |
5. Packaging & Delivery
Package : 100g/bag,or at customer's requirements
Storage: Store in a cool, dry place and keep away from direct strong light.
Shelf Life :2 years
