Pimobendan CAS 74150-27-9

Pimobendan (INN, or pimobendane; tradenames Vetmedin, Acardi, and Heartmedin) is a veterinary medication.Pimobendan is a positive inotrope (increases myocardial contractility).

Product Details

Pharmaceutical Intermediates Pimobendan White Power 


Our company is a professional pharmaceutical raw material factory in China for over 10 years, all powders are factory directly supplying. we have a standardized laboratory, all of our products have to be tested in professional lab before selling, it must meet the in-house quality control standard. whatsapp+8613302415760 email cindy1114@yccreate.com



Pimobendan Basic Info


Product NamePimobendan
Aliaspimobendane, tradenames Vetmedin, Acardi, Heartmedin
CAS74150-27-9
MFC19H18N4O2
MW334.37
EINECS211-390-9
Assay99.0%
PHYSICAL STATEwhite crystalline powder
Usagea cardiotonic agent. antiviral
StorageStore in cool and dry places, keep away from strong light
Package methodshundreds of disgusied pacakges
After-sales serviceWarm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
Shipping methodFedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.
Delivery timedelivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking
Payment MethodsWestern union, money gram, bitcoin and bank transfer


Pimobendan Descrption


Pimobendan is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilatoreffects.


Pimobendan cardiotonic agent. A study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by blocking phosphodiesterase III and potassium channel. Pimobendan's potent venodilating action makes it an appropriate treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.


Pimobendan Application


Pimobendan sensitizes and increases the binding efficiency of cardiac troponin in the myofibril to the calcium ions that are already present in systole. In normal hearts it increases the consumption of oxygen and energy to the same degree as dobutamine but in diseased hearts it may not. 


Pimobendan also causes peripheral vasodilation by inhibiting the function of phosphodiesterase III. This results in decreased resistance to blood flow through systemic arterioles, which decreases afterload (decreases the failing heart's workload) and reduces the amount of mitral regurgitation.


Pimobendan powder


Pimobendan COA


ItmsStandardResults
DescriptionWhite or slightly yellowish powderWhite or slightly yellowish powder
IR IndentificationThe infrared absorption spectrum is concordant with the reference spectrum of standardConform
Heavy metals≤10ppm<10ppm
Melting pointAbout 242℃244℃
SolubilityPractically insoluble in water, freely soluble in dimethylformamide, slightly solulbe in acetone and in methanolConform
Sulphated Ash≤0.1%0.05%
Solvent ResidueEthanol ≤2000ppm300ppm
Particle size98% pass through ASTM 40#screem100%
Related substances

Single impurity A: ≤0.1%

Single impurity B: ≤0.1%

Other impurity: ≤0.1%

Total impurities: ≤0.2%

Conform
Assay≥98.0%99.8%
Water≤1.0%<1.0%
ConclusionMeet the requirements of EP6.0


Packaging & Shipping

 

a.  Aluminum foil bag: 1 kg/bag, 2kg/bag, 5kg/bag, with plastic bags inside, aluminum bag outside;

b.  Cardboard drum: 25 kgs/drum, with double layers plastic bags inside, external use cardboard drums.

c.  Customized by customers.

The shipping term: can be by sea, by air, and sample or small quantity can be shippedby DHL, FEDEX, EMS and TNT.

 

Storage: Store in a well-closed container away from moisture and direct sun light.

Shelf Life: 2 years if store right.


Our Service 


140


FAQ

Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
Q2: How to contact with us?
then send us message the product you interest in, you will get reply within 24 hours.
 
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
 
Q4:Can you give me a discount price?
Surely,It depend on your qty
 
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


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