Metadoxine Powder

Product Details

Pharmaceutical Metadoxine powder CAS:74536-44-0

Any needs contact:

whatsapp:+8613378646535

emails:eleven11@chembj.com

Product Name:Metadoxine

Another Name:5-oxo-L-proline, compound with 5-hydroxy-6-methylpyridine-3,4-

CAS:74536-44-0

Molecular Weight:298.

Molecular Formula:C8H11NO3·C5H7NO3

Chemical Properties Off-White Powder

Usage :Used for treating patients for liver functional disorders in performing stomatologic interventions and in treatment of acute and chronic alcoholism .

assay:98%min

Package:25kg/drum

Medical uses:

Treatment for acute alcohol intoxication

In animal studies, metadoxine increased the activity of acetaldehyde dehydrogenase enzyme, prevented the decrease in alcohol dehydrogenase activity in chronic ethanol-fed rats, accelerated plasma and urinary clearance of ethanol, inhibited the increase of fatty acid esters in the liver of ethanol-treated rats, prevented the formation of fatty liver in rats exposed to a dose of ethanol sufficient to induce fatty liver, increased glutathione levels in the hepatocytes of acutely and chronically alcohol-intoxicated rats, prevented glutathione depletion, lipid peroxidation damage, collagen deposition, and TNF-α secretions induced by alcohol and acetaldehyde in hepatocytes and hepatic stellate cells.

Treatment for liver disease:

Metadoxine may block the differentiation step of preadipocytes by inhibiting CREB phosphorylation and binding to the cAMP response element, thereby repressing CCAAT/enhancer-binding protein b during hormone-induced adipogenesis.Metadoxine, when given in an immediate release form in doses from 300 mg twice a day to 500 mg three times a day of up to 3 months, has been shown to improve biochemical indices of liver function as well as reduce ultrasonic evidence of fatty liver disease.

Shipping & Delivery

1.Packages are generally dispatched within approximately 2 days after receipt of payment.

2.After the each shipping we will provide you with:

1) a link & tracking number to track your package online.

2) the few pictures with your order & details.

3.About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.

4.We confirm 99% clearance,100% resending.

5.Is it the best & safest shipping for all our repeat customers!

Packing Details

Discreet packing ways as your requirement, 100% go through.

Storage

Store in cool and dry area and keep away from direct sunlight.oC