Levodopa L-DOPA

Levodopa, also called L DOPA , is an amino acid created through biosynthesis from the amino acid L Tyrosine in the human body and can also naturally made by plants and animals

Product Details


Levodopa L-DOPA CAS 59-92-7



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Levodopa L-DOPA Basic Info


Product NameLevodopa
AliasL-dopa
CAS59-92-7
MFC9H11NO4
MW197.19
EINECS200-445-2
Assay99.0%
PHYSICAL STATEwhite crystalline powder
Usagetreatment of Parkinson’s symptoms
StorageStore in cool and dry places, keep away from strong light
Package methodshundreds of disgusied pacakges
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Levodopa L-DOPA Descrption


Levodopa is a naturally occurring dietary supplement and psychoactive drug found in certain kinds of food and herbs (e.g., Mucuna pruriens, or velvet bean), and is synthesized from the amino acid L-tyrosine in the mammalian body and brain.


L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines.


Aside from its natural and essential biological role, L-DOPA is also used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia. When used in a pharmaceutical context, the INN designation 'levodopa' is normally used.


Levodopa L-DOPA Application


Levodopa is employed to boost dopamine levels for the treatments for Parkinson's ailment and also dopamine-responsive dystonia, as it is capable of combination your blood-brainhurdle, while dopamine themselves can't. After levodopa features joined the neurological system (CNS), it is metabolized to dopamine simply by savoury L-amino chemical p decarboxylase. Pyridoxal phosphate (vitamin and mineral B6) is often a necessary cofactor with this decarboxylation, and may become administered in addition to levodopa, generally since pyridoxine.

Levodopa's ramification dopamine is a form of important nervetransmitter. Dopamine can't pass the brain blood vessels hurdle and also enter into brain muscle, Nevertheless levodopa can perform this specific,and also variety directly into dopamine inside mental faculties tissues.This fianlly skyrocket ethe dopamine articles and obtain the therapy efficiency regarding Parkinsonism.


Moreover, L-dopa is effective in enhancing the over-all brain function as we know dopamine alone is a mood, attention and movement regulator. According to some users, it is mood and mental outlook uplifting by lessening negative thoughts and converting it to positive ones and causes mental alertness and high energy and motivation level. It therefore serves as a nootropic or brain enhancer.


Levodopa also offers a great many other functions, such as treating crura lively malady,liver stupor,cobalt toxicosis,manganese toxicosis,along with lunacy,cardiovascular failure,canker, hair loss, support erotic operate and so on.


What is the levodopa dosage?


It is advisable that for starters, start using it in a low dosage specifically 100mg and may increase depending on its effect on your body. Then, for those with Parkinson’s disease, it is also advisable to take in 250-500mg L-dopa daily. Also, cycle L dopa every few weeks so the body will not begin to produce less dopamine. And if levodopa is discontinued to use due to side effects, then it is recommended to have gradual dosage reduction. Abrupt discontinuation can cause worsening of PD. So, consult your doctor for further instructions on your dosage.


COA of the Levodopa


Analysis ItemSpecificationResult
Appearance:A white or slightly creamy Crystalline powder.OdorlessConforms
Solubility:Slight soluble in water,practically
insoluble in alcohol and in ether.
Conforms
Identification:PositivePositive
Acidity or alkalinity PH:PH4.5~7.05.15
Light absorption:137°C~147°C142°C
Optical rotation:-1.27°~-1.34°-1.31°
Heavy metals:≤10ppm≤10ppm
Related substances:≤0.50%0.40%
Loss on drying:≤1.0%0.33%
Sulphated ash:≤0.1%0.1%
Assay:99.0~101%

99.1%



Levodopa powder



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