Lamotrigine CAS 84057-84-1

Lamotrigine, originally marketed as Lamictal and available under many brands worldwide, is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder.

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High Quality Pharmaceutical Material Lamotrigine CAS 84057-84-1


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Lamotrigine Basic Info


Product NameLamotrigine
AliasLAMICTAL,LAMOTRIGIN, LAMOTRIGINE
CAS84057-84-1
MFC9H7Cl2N5
MW256.09
EINECS281-901-8
Assay99.0%
PHYSICAL STATEWhite Crystalline Powder
UsageAn anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents.
Storagekeep in cool, dry place
Package methodshundreds of disgusied pacakges
After-sales serviceWarm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
Shipping methodFedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.
Delivery timedelivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking
Payment MethodsWestern union, money gram, bitcoin and bank transfer

Lamotrigine Descrption


Lamotrigine is one of a small number of FDA-approved therapies for seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy. 


Lamotrigine is approved in the US for the treatment of partial seizures.  is considered a first-line drug for primary generalised tonic-clonic seizures (includes simple partial, complex partial and secondarily generalised seizures), and as an adjuvant therapy in partial seizures (focal onset tonic-clonic, atypical absence, myoclonic, and due to Lennox-Gastaut syndrome). As well, it is used as an alternative drug for absence seizure and atypical absence, myoclonic, and atonic seizures.


Lamotrigine Application


Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.


Lamotrigine is a synthetic phenyltriazine with anti-epileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.


lamotrigine has also been successful in controlling rapid cycling and mixed bipolar states in persons with more serious psychiatric disorders and who have not received what is considered to be adequate relief from lithium, carbamazepine or valproate, because it is deemed to possibly have significantly more antidepressant potency than either carbamazepine or valproate.



Lamotrigine powder



Lamotrigine COA:


ItemRequirementsTest Results
DescriptionA white or almost white crystalline powderComplies
SolubilitySoluble in methanol, very slightly soluble in acetone and isopropanol .Complies
Melting point215°C~ 219°C217°C~218°C
Appearance of solution5.0% solution in DMF should be clearComplies
Loss on drying≤ 0.5%0.03%
Residue on ignition≤ 0.1%0.04%
Heavy metals≤ 20ppmComplies
Residual solvent

Methanol≤ 1000ppmComplies
Ethanol≤ 1000ppmComplies
Any other individual impurity:≤ 0.1%Complies
Total impurities≤ 1.0%Complies
Assay99.0%-101.0%99.70%
ConclusionMeets the Requirements


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