High Quality Pharmaceutical Material Lamotrigine CAS 84057-84-1
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Lamotrigine Basic Info
|PHYSICAL STATE||White Crystalline Powder|
|Usage||An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents.|
|Storage||keep in cool, dry place|
|Package methods||hundreds of disgusied pacakges|
|After-sales service||Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.|
|Shipping method||FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.|
|Delivery time||delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking|
|Payment Methods||Western union, money gram, bitcoin and bank transfer|
Lamotrigine is one of a small number of FDA-approved therapies for seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy.
Lamotrigine is approved in the US for the treatment of partial seizures. is considered a first-line drug for primary generalised tonic-clonic seizures (includes simple partial, complex partial and secondarily generalised seizures), and as an adjuvant therapy in partial seizures (focal onset tonic-clonic, atypical absence, myoclonic, and due to Lennox-Gastaut syndrome). As well, it is used as an alternative drug for absence seizure and atypical absence, myoclonic, and atonic seizures.
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.
Lamotrigine is a synthetic phenyltriazine with anti-epileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.
lamotrigine has also been successful in controlling rapid cycling and mixed bipolar states in persons with more serious psychiatric disorders and who have not received what is considered to be adequate relief from lithium, carbamazepine or valproate, because it is deemed to possibly have significantly more antidepressant potency than either carbamazepine or valproate.
|Description||A white or almost white crystalline powder||Complies|
|Solubility||Soluble in methanol, very slightly soluble in acetone and isopropanol .||Complies|
|Melting point||215°C~ 219°C||217°C~218°C|
|Appearance of solution||5.0% solution in DMF should be clear||Complies|
|Loss on drying||≤ 0.5%||0.03%|
|Residue on ignition||≤ 0.1%||0.04%|
|Heavy metals||≤ 20ppm||Complies|
|Any other individual impurity:||≤ 0.1%||Complies|
|Total impurities||≤ 1.0%||Complies|
|Conclusion||Meets the Requirements|