Isotretinoin CAS: 4759-48-2
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Keywords: Isotretinoin; CAS: 4759-48-2
1. Product IntroductionProduct Name: Isotretinoin
2. Product description:Isotretinoin ,also known as 13-cis-retinoic acid, is an oral pharmaceutical drug primarily used to treat severe nodular acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.
Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 2-3 weeks), dry lips (cheilitis), dry and fragile skin, and anincreased susceptibility to sunburn. Uncommon and rare side effects include muscle aches and pains , and headaches. Isotretinoin is known to cause birth defects due to in utero exposure because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development.
3. Isotretinoin COA
|Description||Yellow crystalline powder||White crystalline powder|
|Organic Volatile Impurity||Complies||Complies|
|Loss on drying||≤0.5%||0.18|
|residue on ignition||≤0.1%||0.05%|
|Limit of Tretinoin||≤0.1%||0.18%|
|CONCLUSION:CONFORM TO THE SPECIFICATION OF USP30.|
4. Isotretinoin Applications:
Medical applications: the lack of nutrition of the elderly, thin, for severe burns and had the operation people.
Sports purpose: promote muscle growth, increased training and endurance training load, it has never been proved.
Adaption: Trauma, chronic infection, malnutrition and wasting disease and All kinds of refractory anemia.
As the retinoid, there are strong and fast proliferation inhibition and differentiation of skin gland cell function, effective on severe nodular cystic acne. The gastrointestinal absorption is better, while the local medication invalid. Other drugs used to treat invalid serious acne, cystic acne, acne conglobata, rosacea, ichthyosis, keratosis follicularis and pityriasis rubra pilaris and other skin diseases also have a certain effect.
For severe acne. Anti skin dyskeratosis medicine. For the treatment of severe acne and other disorders.
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6. Order Process:
7. The quality control process:
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
Four steps: sampling, sample pretreatment, measuring and data processing.
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.