Imatinib CAS 152459-95-5

Imatinib is a 2-phenylaminopyrimidine derivative that functions as a specific inhibitor of a number of tyrosine kinase enzymes.

Product Details


Pharmaceutical Raw Material Imatinib White Powder For Anti Cancer


We are a professional company aimed at pharmacy raw material, like anti-depression drug raw material , anti acne drug raw material, antibiotic raw material, Nootropics Drug raw material, Local Anaesthetic Agents,  etc.

No min order, you can be our customer even you only want 1gram to test. Also great discount can be given for bulk orders.

Welcome inquiry, wish we can build long time cooperation.

whatsapp+8613302415760  email cindy1114@yccreate.com



Imatinib Basic Info


Product NameImatinib
CAS152459-95-5
MFC29H31N7O
MW493.6
EINECS604-855-6
Assay99.0%
PHYSICAL STATEwhite crystalline powder
UsageA tyrosine kinase inhibitor, Anti tumor 
StorageStore in cool and dry places, keep away from strong light
Package methodshundreds of disgusied pacakges
After-sales serviceWarm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
Shipping methodFedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.
Delivery timedelivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking
Payment MethodsWestern union, money gram, bitcoin and bank transfer


Imatinib Descrption


Imatinib, sold under the brand names Gleevec and Glivec, used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). 


Imatinib is an antineoplastic agent used to treat chronic myelogenous leukemia. Imatinib is a 2-phenylaminopyrimidine derivative that functions as a specific inhibitor of a number of tyrosine kinase enzymes. 


Imatinib Application


Imatinib is a tyrosine-kinase inhibitor. It kills cancer cells by blocking the action of tyrosine kinases. In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. 


 Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis). Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy-only cancer cells are killed through the drug's action.


imatinib (imatinib, Glivec) had been approved in Switzerland for being used as first-line drug for the treatment of early-stage adult chronic myelogenous leukemia and can also be applied to patients with various types of chronic granulocytic leukemia. 


Imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.


Imatinib COA


QCSEnterprise Standard
TESTSTANDARDRESULTS
AppearanceWhite or almost white powderWhite powder
SolubilityEasy to dissolve in the waterComplies
IdentificationHPLCAlmost the same
infrared absorptionAlmost the same
Melting point224--229ºC222.3--224.5ºC
Methane sulphonic acid16.1-16.5%16.2%
heavy metals≤20ppm<10ppm
residue on igniton≤0.1%0.03%
Related impuritySigle impurity ≤0.2%0.06%
Total impurity no more than 1.0%0.40%
Assay(HPLC)98.0%--102.0%99.60%
ConclusionComplies With Enterprise Standard

Imatinib raw


F. A. Q


Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Moneygram

Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7 Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship

Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.

We have formed a technology and management team that cooperate closely with some overseas Labs all speak highly of our safe shipping and goods .
please donot hesitate to contact us.

whatsapp+8613302415760 email cindy1114@yccreate.com


Shipping and Delivery

 

1. Packages are generally dispatched within approximately 2days after receipt of payment.

2. After the each shipping we will provide you with

3. tracking number to track your package online.

4. the few pictures with your order &?details.

5. About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.

6. We confirm 99% clearance,100% resending.

7. Is it the best and safest shipping for all our repeat customers!


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