Pharmaceutical Alprostadil (PGE1)/Prostaglandin E1 CAS 745-65-3
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Alprostadil (PGE1)/Prostaglandin E1 CAS 745-65-3
Product Name: Alprostadil
Appearance: White Powder
Mini order: 10grams
Quality standard: USP/EP/JP
Alprostadil Injection, USP for intravascular infusion contains 500 micrograms Alprostadil, more commonly known as prostaglandin E1, in 1 mL dehydrated alcohol.
The chemical name for Alprostadil is (1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxy-1-octenyl]-5-oxocyclopentane heptanoic acid, and the molecular weight is 354.49.
Alprostadil is a white to off-white crystalline powder with a melting point between 110° and 116° C. Its solubility at 35° C is 8000 micrograms per 100 mL double distilled water.
Alprostadil is a type of medicine that causes blood vessels to expand, increasing blood flow throughout the body. By increasing blood flow to the penis, alprostadil helps facilitate an erection.
Alprostadil can be given either by injection or as a suppository. When given as a suppository, the drug is placed into the opening at the tip of the penis. When injected, a needle and syringe is used to inject the drug directly into the penis.
If you receive the injection-form, alprostadil is sold under the brand names Caverject, Edex, and Prostin VR. Suppository-form of alprostadil is sold under the brand name MUSE (Medicated Urethral System for Erection).
Alprostadil should only be used in men with erectile dysfunction. If this drug is not used properly, permanent damage to the penis can occur.
What is Alprostadil?
Alprostadil injection is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. Such congenital heart defects include pulmonary atresia, pulmonary stenosis, tricuspid atresia, tetralogy of Fallot, interruption of the aortic arch, coarctation of the aorta, or transposition of the great vessels with or without other defects.
1.Alprostadil is used in maintaining a patent ductus arteriosus in newborns.
2. Alprostadil is also as urethral suppositories and in injectable form.
3.Alprostadil is also used for critical limb ischemia.
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