Acitretin /Soriatane / Neotigason Powders

Acitretin is a second generation retinoid. It can be taken orally, which is typically utilized for psoriasis. It is just a metabolite of etretinate, which was used before the introduction of acitretin. They induce keratinocyte differentiation minimizing epidermal hyperplasia.

Product Details


1.Product Introduction

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2.Specifications:


Product Name:AcitretinChinese Name:Aquting
CAS NO:55079-83-9 Other Name:
7-dimethyl-2,4,6,8-nonatetraenoic acid; Neotigason; Soriatane; acitretin 
MF:C21H26O3MW:326.43
Assay:99%Test Method:HPLC
Appearance:Yellow or Greenish Yellow Crystalline Powder

Physical Property:Melting Point 228~230℃
Function:Be used in the treatment of hyperkeratotic skin diseases such as psoriasis



3.Applications:



Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis.Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments.

It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.

Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects.


Acitretin Usage

To the treatment of psoriasis (severe refractory cases, including erythrodermic andgeneralized pustular), severe refractory oral lichen planus, keratosis refractory severeintractable disorders(including ichthyosis-like skin disease, congenital ichthyosis-likeerythroderma, lamellar ichthyosis as well as other ichthyosis), follicular keratosis, palmoplantarkeratosis, pityriasis rubra pilaris, palmoplantar pus fibromatosis.


Effect

Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently.Men and women who use it should not donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss.

To the treatment of psoriasis (severe refractory cases, including erythrodermic andgeneralized pustular), severe refractory oral lichen planus, keratosis refractory severeintractable disorders (including ichthyosis-like skin disease, congenital ichthyosis-likeerythroderma, lamellar ichthyosis as well as other ichthyosis), follicular keratosis, palmoplantarkeratosis, pityriasis rubra pilaris, palmoplantar pus fibromatosis.


4.prodection details


Yam khoom

Specifications

Ntsiab lus

Kev piav qhia

Lub daj lossis xim ntsuab-daj, crystalline hmoov

Conforms

Qhia txog

Yuav tsum ua raws li

Txhua tus ua raws li

Poob rau ziab

≤0.5%

0.1%

Sulphated Tshauv

≤0.1%

0.04%

Hnyav hlau

≤0.002%

<>

Palladium

≤0.001%

Tsis yog kuaj xyuas

Tshaj loj npaum li casTis densityLoose ceev

100% <>

Conforms0.386g / ml0.205g / ml

Lwm Yam Uas Muaj Feem Xyuam

Tag nrho Impurities

 

≤0.3% ≤1.0%

 

0.23% 0.36%

Kev ntsuam xyuas (ntawm qaug hauv paus)

98% rau102.0%

99.9%

Xaus

Cov kev sib tw muaj raws li cov qauv EP6.0





5. Packaging & Deliveryraw_fat_loss_powders_lorcaserin_hydrochloride_hemihydrate_


Minimum Order Quantity:   Negotiation

Price:Negotiation

Packaging Details:Discreet ways of packing for Customs pass guaranteed(1kg foil bag)

Leading time:Within 8hours after payment.(PS: USA based delievry could be available.)

Delivery time:Within 5working days after payment.

Payment method:Western Union,Money Gram,Bank Transfer,Bitcoin.

Supply Ability:100ton Per Month

Shipment Method: UPS DHL Fedex TNT EMS HKEMS HongKong post EUB ETK



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