Acitretin CAS 55079-83-9 Powder

Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin.

Product Details

Pharmaceutical Raw Materials Acitretin CAS 55079-83-9 For Antipsoriatic 

We are a professional company aimed at pharmacy raw material, like anti-depression drug raw material , anti acne drug raw material, antibiotic raw material, Nootropics Drug raw material, Local Anaesthetic Agents etc.

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Acitretin Quick Details


Product NameAcitretin
Aliasetretin
CAS55079-83-9
MFC21H26O3
MW326.43
EINECS259-474-4
PURITY99.5%
PHYSICAL STATEYellow or greenish-yellow crystalline powder
Usageskin care
Storagekeep in cool, dry place
Package methodshundreds of disgused packages
After-sales serviceWarm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
Shipping methodFedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.
Delivery timedelivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking
Payment MethodsWestern union, money gram, bitcoin and bank transfer

Acitretin Descprtion


Acitretinis widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc.. 


For the treatment of psoriasis (severe refractory cases, including erythrodermic andgeneralized pustular), severe refractory oral lichen planus, keratosis refractory severeintractable disorders (such as ichthyosis-like skin disease, congenital ichthyosis-likeerythroderma, lamellar ichthyosis and other ichthyosis), follicular keratosis, palmoplantarkeratosis, pityriasis rubra pilaris, palmoplantar pus fibromatosis.


Acitretin Application


Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments.


Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days.


Because acitretin can be reverse metabolised into etretinate which has a long half life, women must avoid becoming pregnant for at least 2 years after discontinuing acitretin. Therefore, etretinate is generally not recommended for women of child bearing age with a risk of becoming pregnant.


Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently. Men and women who use it shouldnot donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss.


Acitretin COA:


Analysis contentsAnalysis standard BP2010Analysis results
AppearanceA yellow or greenish-yellow,
crystalline powder
White crystalline powder
IdentificationPositivePositive
Clarity of solutionClearClear
Color of solution≤BY7< BY7
Assay99.0-100.0%99.9%
Loss on Drying≤0.4%0.03%
Residue on ignition≤0.1%0.03%
Sulphate Ash≤0.1%0.03%
Specific rotation+20.5°~ +21.5°+20.96°
PH(with 2% water solution)2.4-2.82.55
PH(with 5% water solution)2.1-2.62.30
Melting rangeAbout 190°C191°C
Heavy Metals≤3ppm<3ppm
Iron≤2ppm<2ppm
Copper≤5ppm<5ppm
Oxalic Acid≤0.2%<0.2%
Arsenic≤1ppm<1ppm
Lead≤3ppm<3ppm
Cadmium≤1ppm<1ppm
Organic volatile impuritiesMeets the requirementsconform

Related Substance


Impurity C ≤0.15%

Impurity D ≤0.10%

Any other Unspecific Impurities Impurity≤0.10%

Total Impurity ≤0.2%


Complies

Total Plate Count≤1,000cfu/g<1, 000cfu/g

Acitretin powder


Packaging & Service


1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 25 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 24 hours as soon as receiving the payment. Updated tracking code will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product.


Rules of Shipping


All our products can be shipped worldwide and to assure the loyalty and discretion of our client we respect the following rules:

We never use in our shipments the name of our company or any content implying pharmacy .

We use designed discreet packing methods according to different countries and quantity, universal and secure.

We practice constant changes in the types of packaging we use, thus achieving a maximum success in delivery procedure.

We use small packages to raise a lower level of susceptibility.

We ship the products in original cardboard boxes to assure a healthy and ecological medium.


how to make order

step1

Pre-sale service

1.As for your every inquiries, we always reply timely and patiently.
All of the relevant information will be provided to
help you to make a wise choice



2. if you need we can offer provide you with COA ,
Cook Recipes Of Steroid Oil , Feedback Of Other Customers

Step2

payment

1.we'd like to accept bank transfer, Western Union , Moneygram , Bitcoin

Step3

delivery

2.we are support Transportation: DHL, UPS, TNT, EMS,
Hongkong EMS, FedEx or Other



3.After confirming your payment, shipping arrangement
and package pictures will be provided within 24 Hours ;
Tracking number will be provided within 72 Hours.



4.For important parcel information, such as:
Left Original Country , Arrived At Destination Country ,
Passed Customs , Out For Delivery , Delivered,
those information will be sent to you timely.

Step4

After-sales
service

1.you could consult us for any questions,
we offer 7*24h good servies and Tech-support.

 

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