Pharmaceutical Raw Materials Acitretin CAS 55079-83-9 For Antipsoriatic
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Acitretin Quick Details
|PHYSICAL STATE||Yellow or greenish-yellow crystalline powder|
|Storage||keep in cool, dry place|
|Package methods||hundreds of disgused packages|
|After-sales service||Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.|
|Shipping method||FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way.|
|Delivery time||delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking|
|Payment Methods||Western union, money gram, bitcoin and bank transfer|
Acitretinis widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
For the treatment of psoriasis (severe refractory cases, including erythrodermic andgeneralized pustular), severe refractory oral lichen planus, keratosis refractory severeintractable disorders (such as ichthyosis-like skin disease, congenital ichthyosis-likeerythroderma, lamellar ichthyosis and other ichthyosis), follicular keratosis, palmoplantarkeratosis, pityriasis rubra pilaris, palmoplantar pus fibromatosis.
Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments.
Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days.
Because acitretin can be reverse metabolised into etretinate which has a long half life, women must avoid becoming pregnant for at least 2 years after discontinuing acitretin. Therefore, etretinate is generally not recommended for women of child bearing age with a risk of becoming pregnant.
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently. Men and women who use it shouldnot donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss.
|Analysis contents||Analysis standard BP2010||Analysis results|
|Appearance||A yellow or greenish-yellow,|
|White crystalline powder|
|Clarity of solution||Clear||Clear|
|Color of solution||≤BY7||< BY7|
|Loss on Drying||≤0.4%||0.03%|
|Residue on ignition||≤0.1%||0.03%|
|Specific rotation||+20.5°~ +21.5°||+20.96°|
|PH(with 2% water solution)||2.4-2.8||2.55|
|PH(with 5% water solution)||2.1-2.6||2.30|
|Melting range||About 190°C||191°C|
|Organic volatile impurities||Meets the requirements||conform|
Impurity C ≤0.15%
Impurity D ≤0.10%
Any other Unspecific Impurities Impurity≤0.10%
Total Impurity ≤0.2%
|Total Plate Count||≤1,000cfu/g||<1, 000cfu/g|
Packaging & Service
1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 25 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 24 hours as soon as receiving the payment. Updated tracking code will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product.
Rules of Shipping
All our products can be shipped worldwide and to assure the loyalty and discretion of our client we respect the following rules:
We never use in our shipments the name of our company or any content implying pharmacy .
We use designed discreet packing methods according to different countries and quantity, universal and secure.
We practice constant changes in the types of packaging we use, thus achieving a maximum success in delivery procedure.
We use small packages to raise a lower level of susceptibility.
We ship the products in original cardboard boxes to assure a healthy and ecological medium.
how to make order
1.As for your every inquiries, we always reply timely and patiently.
2. if you need we can offer provide you with COA ,
1.we'd like to accept bank transfer, Western Union , Moneygram , Bitcoin
2.we are support Transportation: DHL, UPS, TNT, EMS,
3.After confirming your payment, shipping arrangement
4.For important parcel information, such as:
1.you could consult us for any questions,