PRL-8-53 HCL CAS.51352-87-5

PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska.

Product Details

99% Nootropic powder Prl-8-53 HCl CAS 51352-87-5

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Keywords: PRL-8-53, PRL-8-53 HCL,


1. Product Introduction

Data of PRL-8-53 HCL Powder

PRL-8-53 HCL Product Name: PRL-8-53 HCL
PRL-8-53 HCL CAS: 51352-87-5
PRL-8-53 HCL MF: C18H22ClNO2
PRL-8-53 HCL MW: 319.8258
PRL-8-53 HCL Purity: 99%
PRL-8-53 HCL BP: 398.9°C at 760 mmHg
PRL-8-53 HCL FP: 134°C
PRL-8-53 HCL Grade: Pharmaceutical Grade
PRL-8-53 HCL Appearance: White Powder


2. Product description:

PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects.


But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.

PRL-8-53 HCL (2)


3. COA:

Product name

PRL-8-53 HCL

CAS No.

51352-87-5

Outer Packing

1KG

Production date

2018.07.04

Shelf life

2020.07.03

Standard adopted

In-house standard

Items of analysis

Specification

Results

Appearance

Off white solid powder

Conform

Identification

Conform with NMR

Conforms

Melting Point

149-152℃

150-151℃

Loss on Drying

≤0.50%

0.23%

Residue on ignition

≤1.0%

0.28%

Purity(HPLC)

≥99%

99.66%

Heavy metals

NMT 20PPM

Conforms

Conclusion

Qualified


4. Applications:
PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.

Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.


5. Dosages:

The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.


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-Parcel will be delivered in 4-5 working days


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PRL-8-53 HCL (3)

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