Nootropice products Vinpocetine raw powder for brain improvement
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Product name: Vinpocetine
Plant Origin: voacanga seed extract
CAS NO. : 42971-09-5
Molecular weight: 350.45
Mocecular formula: C22H26N2O2
Appearance: light yellow to off-white powder
(1) Vinpocetine is a cerebrovascular expansion drug and has a relatively stronger function than Vincamine. It can selectively increase cerebral blood flow, enhance and improve brain oxygen supply, promote metabolism, enhance the capacity of deformation for red blood cells, reduce blood viscosity, inhibit platelet aggregation, improve tissue metabolism.
(2) Vinpocetine is mainly used in the treatment of cerebral infarction sequela, cerebral hemorrhage sequelae, cerebral arteriosclerosis, etc. It can also used in the treatment of retinal vascular sclerosis and blood vessel spasm, the elderly deafness, and dizziness.
(3) Vinpocetine is a half synthetic Vincamine derivative, and has the similar effect with Vincamine. It has a stronger expansion function for cerebrovascular selectively.
1)VINPOCETINE is a semisynthetic derivative alkaloid of vincamine, and also can be semisynthesized from tabersonine, an extract from Voacanga Africana Seed.
2)Clinical studies suggest that it facilitates cerebral metabolism by improving cerebral blood flow, increasing glucose and oxygen utilization by neurons and concentration of neurotransmitters involved in the process of memory formation.
3)Clinical studies have also shown that Vinpocetine may help to maintain healthy microcirculation in the inner vital organs of ears and eyes.
4)Research has shown that the effects of this compound go beyond mere prevention and turn it into a Powerful Memory Enhancer.
Vinpocetine has been clinically used in many countries for treatment of cerebrovascular disorders such as stroke and dementia for more than 30 years. Due to its excellent safety profile, increasing efforts have been put into exploring the novel therapeutic effects and mechanism of actions of vinpocetine in various cell types and disease models. Recent studies have revealed a number of novel functions of vinpocetine, including anti-inflammation, antagonizing injury-induced vascular remodeling and high-fat-diet-induced atherosclerosis, as well as attenuating pathological cardiac remodeling. These novel findings may facilitate the repositioning of vinpocetine for preventing or treating relevant disorders in humans.
Recommend Dosage :
Take Vinpocetine with meals to enhance absorption.
The standard low dose is 5mg of Vinpocetine at each of these three meals, with 20mg per meal seen as a high dose. This dose range is suitable for the purposes of neuroprotection, enhancing cerebral blood flow, and reducing the rate of cognitive decline.
IV administration of Vinpocetine can cause serious adverse effects, such as death from sudden falls in blood pressure and heart rate (R, R2). However, this is not an issue with oral Vinpocetine at the standard dosages.
There have been reports of skin allergy to vincamine (R).
There was also one report of a sudden drop in white blood cell count at 15mg per day (R).
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