​Coluracetam CAS:135463-81-9 Raw Powder

Coluracetam CAS:135463-81-9 Raw Powder China Steroid Raws/ Sarms/ Peptides sell on line. If you want to know more details, please contact Jason on: Email: jason168@yccreate.com WhatsApp:+8618042849221 Keywords: Coluracetam, CAS:135463-81-9 1. Product Introduction Product name: Coluracetam...

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Coluracetam CAS:135463-81-9 Raw Powder

 

China Steroid Raws/ Sarms/ Peptides sell on line. If you want to know more details, please contact Jason on: Email: jason168@yccreate.com  WhatsApp:+8618042849221

 

Keywords: Coluracetam, CAS:135463-81-9

 

1. Product Introduction

Product name: Coluracetam
Specification: 99%
CAS No.: 135463-81-9
Appearance: White powder
Molecular Formula: C19H23N3O3
Molecular Weight: 341.4042

Brivaracetam (3)


2. Product description:

Coluracetam is a nootropic drug of the racetam family. Coluracetam was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California. Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD). BrainCells Inc is currently out-licensing the drug for this purpose. It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.


3. Coluracetam COA:

Analysis TestSpecificationResult
DescriptionWhite crystalline powder, odorlessConform
SolubilityEasily soluble in water, unsoluble in ethanolConform
PH6.0~7.56.9
Solution clarity and colorSolution should be clear and colorlessConform
Related substances5'CMP 0.3%
Simple impurity
Total other impurity
0.01%
0.03%
0.10%
Chloride0.05%Conform
Ammonium0.05%Conform
Fe0.01%Conform
Phosphate0.1%Conform
Loss on drying≤6.0%1.3%
Heavy metals0.002%Conform
Arsenide0.0001%Conform
Bacterial Endotoxins0.3EU/mgConform
Microbial LimitConformConform

 

4. Coluracetam Benefits

(1)Memory and Learning

Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same results are expected in human beings. A study conducted by BrainCells Inc, showed a memory improvement in rats who were given substance AF64A (a neuron-specific neurotoxin) for 8 days along with Coluracetam in 3mg doses. These rats were put through the standardized Morris Water Maze to mark their ability to get through it, and even up to 72 hours after the last 8mg dose, they were still able to. Another key finding of this study was that the results were still apparent 3 days after the last dose, even though the serum concentration of Coluracetam was negligible.
(2)Depression and Anxiety
BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with GAD (generalized anxiety disorder). However, the differences were most pronounced in those who didn't find relief in using standard antidepressants. After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved scores during a depression assessment test.
(3)Eyesight
Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn't any conclusive evidence to support the mechanisms behind this benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.


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