Brivaracetam CAS:357336-20-0 Raw Powder
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Keywords: Brivaracetam, CAS:357336-20-0
1. Product Introduction
Product Name:Brivaracetam2. Product description:
Brivaracetam (trade name Briviact), a chemical analog of levetiracetam, is a racetam derivative with anticonvulsant (antiepileptic) properties. Briviact (brivaracetam) is a selective, high-affinity synaptic vesicle protein 2A ligand and analog of levetiracetam indicated for the treatment of partial-onset seizures in patients with epilepsy.
3. Brivaracetam COA:
ITEMS | SPECIFICATION | TESTRESULTS |
Appearance | Off-white or white powder | Conforms |
Identification | HPLC,NMR;LC-MS | Conforms |
Related substances | Individual impurity≤0.5% | 0.09% |
Total impurities≤1.0% | 0.20% | |
Loss on drying | ≤0.5% | 0.3% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤10ppm | Conforms |
Assay | ≥98.0 % | 99.1% |
4. Brivaracetam Benefits
Brivaracetam, a chemical analog of Levetiracetam, is a racetam derivative with anticonvulsant effect. It is used for the treatment of partial-onset seizures with or without secondary generalisation, in combination with other antiepileptic drugs. The exact mechanism of brivaracetam's anti-epileptogenic activity is unknown. What is known is thatbrivaracetam binds SV2A with high affinity. SV2A is known to play a role in epileptogenesis through modulation of synaptic GABA release. It is thought that brivaracetam exerts its anti-epileptogenic effects through its binding to SV2A. Brivaracetam can also inhibit Na+ channels which may also contribute to its anti-epileptogenic action .
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