Triamcinolone CAS.76-25-5

Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, relieve the discomfort of mouth soresand in nasal spray form as an over-the-counter relief for allergic and perennial allergic rhinitis. It is a more potent derivative of triamcinolone, being about 8 times as potent as prednisone.

Product Details

Pharmaceutical Raw Material Triamcinolone Acetonide For Skin Care

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Quick Details

Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, relieve the discomfort of mouth soresand in nasal spray form as an over-the-counter relief for allergic and perennial allergic rhinitis. It is a more potent derivative of triamcinolone, being about 8 times as potent as prednisone.


Product Name: triamcinolone acetonide
CAS: 76-25-5
Molecular formula: C24H31FO6
Molecular weight: 434.49800
Exact mass: 434.21000
PSA: 93.06000
LogP: 2.41880
Physical and chemical properties
Appearance and properties: white to off-white crystalline powder
Density: 1.33 g / cm3
Melting point: 274-278ºC (dec.)
Boiling point: 576.9ºC at 760 mmHg
Flash point: 302.7ºC
Refractive index: 1.588
Stability: flammable. Incompatible with strong oxidizing agents.
Storage conditions: Treasury ventilation low temperature drying, separate storage with food raw materials
Security Information

Usage: Corticosteroids, acting on glucose metabolism, can reduce the antibody tissue damage caused by the pathological response, for active rheumatism and rheumatoid arthritis.


Triamcinolone(3)


Application:

Triamcinolone acetonide as an intra-articular injectable has been used to treat a variety of musculo skeletal conditions. When applied as a topical ointment, it is used for blistering from poison ivy, oak, and sumac, applied to the skin, avoiding eyes, mouth, and genital area. It provides immediate relief and is used before using oral prednisone. Oral/dental paste preparations are used for treating aphthous ulcers.


Triamcinolone acetonide is also used in veterinary medicine as an ingredient in topical ointments and in topical sprays for control of pruritus in dogs.A series of injections with triamcinolone acetonide or another corticosteroid may reduce keloid size and irritation. It is also used as a preinductor and/or inductor of birth in cows.


Uncommonly, intramuscular injection of triamcinolone acetonide may be indicated for the control of severe or incapacitating allergic states for which conventional treatments have failed, such as asthma, atopic dermatitis, contact dermatitis, perennial or seasonal allergic rhinitis, serum sickness, and transfusion and drug hypersensitivity reactions.


Specification:

Items

Specifications

Results

Appearance

White or practically white, odorless, crystalline powder

Conforms

Identification

A: IR; B:UV

Conforms

Specific rotation

+65°~+72°

+70°

Loss on drying

≤2.0%

0.19%

Residue on ignition

≤0.5%

Conforms

Heavy metals

≤0.0025%

Conforms

Assay

97.0%~102.0%

98.8%

Particle size

Micronized

Conforms


Packing and Shipping

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