Hydrocortisone CAS 50-23-7
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Keywords: Hydrocortisone; CAS:50-23-7
1. Product Introduction
Product Name: Hydrocortisone
2. Product description:
Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD.It is the treatment of choice for adrenocortical insufficiency.It can be given by mouth, topically, or by injection.Stopping treatment after long-term use should be done slowly.
Side effects may include mood changes, increased risk of infection, and swelling.With long-term use common side effects include osteoporosis, upset stomach, physical weakness, easy bruising, and yeast infections.While used, it is unclear if it is safe during pregnancy.It works as an antiinflammatory and by immune suppression.
Hydrocortisone was discovered in 1955.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication.The wholesale cost in the developing world is about 0.27 USD per day as of 2014 for the form taken by mouth.In the United States it costs less than 25 USD for a typical month of treatment.
3. Hydrocortisone COA
Items of analysis | Specification | Results |
Characteristics | White or almost white, crystalline powder. | almost white crystalline powder |
Identification | A.IR-spectrum B.HPLC C.TLC | Conforms |
Loss on drying | ≤1.0% | 0.03% |
Specific Rotation | + 162°~+168° | +165° |
Any other Impurity | ≤0.1% | 0.081% |
Total Impurities | ≤2.0% | 0.46% |
Acetone | ≤5000ppm | ND |
Methanol | ≤3000ppm | 654ppm |
Assay | 97.0%~103.0% | 100.1% |
Particle Size | 90%<30μm | Conforms |
Impurity A | ≤0.2% | 0.02% |
Impurity B | ≤0.2% | <0.02% |
Impurity C | ≤0.5% | 0.03% |
Impurity D | ≤0.5% | <0.02% |
Impurity E | ≤0.5% | <0.02% |
Impurity F | ≤0.3% | 0.03% |
Impurity G | ≤0.4% | 0.08% |
Impurity I | ≤0.5% | <0.02% |
Impurity H | ≤0.15% | <0.02% |
Impurity N | ≤0.15% | <0.02% |
Conclusion | Qualified |
4. Hydrocortisone Applications:
For adrenal insufficiency caused by disease, rheumatoid arthritis, rheumatic fever, gout, bronchial asthma. For atopic dermatitis, seborrheic dermatitis, pruritus. Large doses cause Cushing's syndrome, sodium retention, psychiatric symptoms, digestive ulcers, osteoporosis, growth inhibition.
For iridocyclitis, keratitis, scleritis, conjunctivitis. For neurodermatitis, for tuberculous meningitis, pleurisy, arthritis, tenosynovitis, acute and chronic sprain, strain, etc. sheath. Application Mainly used as anti-inflammatory, anti-allergic, anti-toxin, the role of antibodies grams.
It is mainly used to treat rheumatoid arthritis, rheumatic fever, gout, bronchial asthma. Injection for tuberculous or fester sex meningitis, tuberculosis pleurisy, pyothorax, arthritis, tenosynovitis, tendons strain, sprains, nodular rash, itching flat moss, etc. Eye drops agent used in all kinds of eye inflammation. Frost agent in allergic or seborrheic dermatitis, itch disease, etc.
5. Related Products:
Glucocorticoid Steroid Powder | |
Product Name | CAS NO. |
Dexamethasone | CAS:20-02-2 |
Dexamethasone Sodium Phosphate | CAS:55203-24-2 |
Beclometasone | CAS:5534-09-8 |
Cortisone | CAS:53-06-5 |
Hydrocortisone | CAS:50-03-3 |
Prednisone Acetate | CAS:125-10-0 |
Fluticasone | CAS:948566-12-9 |
mometasone furoate | CAS:83919-23-7 |
Triamcinolone | CAS:76-25-5 |
Beclometasone Dipropionate | CAS:5534-09-8 |
6. Order Process:
7. The quality control process:
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.