Fluticasone Propionate For Strong Anti-inflammatory

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist (Kd = 0.5 nM). Fluticasone propionate potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC50 = 3.7 nM) in vitro. Inhibits mast cell accumulation in nasal mucosa following topical administration. Fluticasone propionate is a lipophilic anti-inflammatory agent.

Product Details


1.Product Introduction

Welcome to contact Morgan for more details.Whatsapp:+8617725670492, email:liuxf@yccreate.com.


2.Specifications:


Product name

Fluticasone propionate

Structure

 Factory supply Fluticasone Propionate CAS 80474-14-2 For Strong Anti-inflammatory And Anti-allergic Effects with best price!

CAS No.

80474-14-2

Molecular Formula

C25H31F3O5S

Molecular weight

500.57

EINECS NO.

617-082-4

Grade Standard

Medicine Grade

COA

Avaliable



3.Applications:


Application :

  • Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein.

  • It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic.

  • Nasal spray preparation of fluticasone propionate is used in the prophylaxis and treatment of allergic rhinitis.

  • Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor.

  • It has been shown to have a wide range of inhibitory effects on multiple cell types and mediators involved in inflammation.

This product of oral 1mg, even after 16mg,6 hours fluticasone propionate without fluorine in blood, the latter of hydrocortisone is still at a low level in the blood, indicated that oral bioavailability and urinary excretion is almost zero. After inhaling the product reached the peak serum concentration of 0.5-1.5 hours, metabolic period was extended for 5 hours, is a long-acting glucocorticoid drugs.

4.prodection details


Item

Specifications

Appearance

White Powder.

Purity

99%min

Melting point

275℃

Specific rotation

D +30° (c = 0.35)

Density

1.31

Refractive index

31°(C=1, Dioxane)

Solubility

DMSO: ≥10 mg/mL

Storage condition

2-8℃

Shelf life

2 years






5. Packaging & Deliveryraw_fat_loss_powders_lorcaserin_hydrochloride_hemihydrate_


  1.Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.

  2. Our products have exported to Germany,Brazil ,USA, , Spain, UK,  France, Canada, Mexico,Poland, Russia,  Australia,                  Norway,Finland,  and many other countries, over 100kgs each month  
 
  3.Professional team special for package and shipment and staring on tracking code 24hours for  customs pass       guaranteed.      
   Most of powders are in stock, Chargeable samples are available, Could be shipped out within  24hours.
   High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS,  UPS, etc. 


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