Tetracaine Pain killer Powder
China Steroid Raws/ Sarms/ Peptides sell on line. If you want to know more details, please contact Jason on: Email : email@example.com WhatsApp：+8618042849221
Keywords: Tetracaine, Amethocaine, Pontocaine, Dicaine, Laudocaine
1. Product Introduction
Product Name: Tetracaine
Alias: Amethocaine; Pontocaine; Dicaine; Laudocaine
Einecs No: 202-316-6
Molecular Formula: C15H24N2O2
Molecular Weight: 264.36
Grade: Pharmaceutical Grade
Appearance: white crytalline powder
2. Product description:
Tetracaine is a weak base, therefore, significant changes in the rate of ionised lipid soluble drug uptake may occur with changes in the acid base balance.
In vitro studies have shown that tetracaine has a high affinity for melanin, therefore, differences in duration of action may be expected between deeply pigmented eyes and less pigmented eyes.
The primary site of metabolism for tetracaine is the plasma. Pseudocholinesterases in the plasma hydrolyse tetracaine to 4-aminobenzoic acid. Unmetabolised drug is excreted in the urine.
Tetracaine hydrochloride is used as a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.
3. Tetracaine COA:
|Test Items||Specification||Test Results|
|Appearance||Fine, white, crystalline, odorless powder||confirm|
|Identification||ABC in Pass||confirm|
|Solubility||Very soluble in water, soluble in Alcohol;|
insoluble in Ether and Benzene
|USP Reference standards||USP Tetracaine Hydrochloride RS |
USP Endotoxin RS.
|Melting point||145~150 degree||146.0~147.5 degree|
|Chromatographic purity||In Pass||confirm|
|Related substance||Not more than the reference solution 0.05%||confirm|
|Residue on ignition||≤0.10%||0.05%|
|Loss on Drying||≤ 0.5%||0.19%|
4. Product Application:
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. 2.Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
5. Related Products:
Local Anesthetic powder