Tetracaine HCL CAS. 136-47-0

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

Product Details

Local Anesthetic Tetracaine HCL CAS 136-47-0 With Good Quality

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Tetracaine HCL Quick Details

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

Tetracaine HCl

Tetracaine HCl Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; Amethocaine hydrochloride

Tetracaine HCl CAS : 136-47-0

Tetracaine HCl Molecular formula: C15H25ClN2O2

Tetracaine HCl Molecular weight: 300.82

Tetracaine HCl EINECS: 205-248-5

Appearance: Fine white crystalline and odorless powder

Melting point: 145~150 degree

Assay: 99%

Grade: Pharmaceutical Grade

Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.


Tetracaine HCL Application

Tetracaine HCL chloride is synthesized from 4-butylaminobenzoic acid. The esterification reaction is carried out by acid catalysis to form ethyl ester. The base-catalyzed transesterification is achieved by boiling ethyl 4-butylaminobenzoic acid with an excess of 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.


Tetracaine HCL (INN, also known as tetracaine; trade names Pontocaine.Ametop and Dicaine) are potent topical anesthetics of the ester groups. It is mainly used for ophthalmology and antipruritic agents and has been used for spinal anesthesia.


In biomedical research, tetracaine is used to alter the function of the calcium release pathway (Lannottine receptor), which controls the release of calcium in intracellular stores. Dicaine is an allosteric blocker for channel function. At low concentrations, tetracaine causes initial inhibition of spontaneous calcium release events, whereas at high concentrations, tetracaine is completely released.


Tetracaine Hydrochloride Dosage:

1. For tonometry and other short procedures: Instill 1 to 2 drops in the eye(s) just prior to evaluation.

2. For minor surgical procedures, such as foreign body or suture removal: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 1 to 3 instillations.

3. For prolonged anesthesia, such as cataract extraction: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 3 to 5 doses.


Tetracaine HCL(4)


Tetracaine HCL Specification

Product Name

Tetracaine hydrochloride(C15H25ClN2O2)

CAS: 136-47-0

Items Tested

Specification

Result

Characters

White crystals or a white crystalline powder

White crystalline powder

Appearance of solution

Clear and colourless

Conform

Chromatographic purity

In Pass

confirm

Solubility

Very soluble in water, soluble in Alcohol;
insoluble in Ether and Benzene

Comfirm

Melting range

145℃~150℃

146℃~147.5℃

Loss on Drying

≤ 0.5%

0.19%

Residue on ignition

≤0.10%

0.05%

Related substance

Not more than the reference solution 0.05%

confirm

Loss on drying

≤0.5%

0.07%

Heavy metals

≤10ppm

confirm

PH

4.5-6.5

5.8

Heavy metals

≤0.0005%

Conform

Sulphated ash

≤0.1%

0.05%

Related substances

≤0.05%

Conform

Assay

99.0-101.0%

99.87%

Storage

Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.


Package

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Delivery

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It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slowpost.


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Local Anesthetic Drugs we supply

Procaine Base

CAS 59-46-1

Lidocaine HCl

CAS 73-78-9

Benzocaine

CAS 94-09-7

Lidocaine Hydrochloride

CAS 51-05-8

Xylocaine Lidocaine

CAS 137-58-6

Tetracaine HCl

CAS 136-47-0

Propitocaine Hydrochloride

CAS 1786-81-8

Aarticaine Hydrochloride

CAS 23964-57-0

Procaine Hydrochloride

CAS 51-05-8

Tetracaine hydrochloride

CAS 136-47-0

Lidocaine Base

CAS 137-58-6

Dyclonine hydrochloride

CAS 536-43-6

Tetracaine Base

CAS 94-24-6

Dibucaine Hydrochloride

CAS 61-12-1

Proparacaine Hydrochloride

CAS 5875-06-9

Ropivacaine Hydrochloride

CAS 98717-15-8

Bupivacaine

CAS 2180-92-9

Bupivacaine Hydrochloride

CAS 14252-80-3

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