Local Anesthetic Tetracaine HCL CAS 136-47-0 With Good Quality
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Tetracaine HCL Quick Details
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
Tetracaine HCl
Tetracaine HCl Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; Amethocaine hydrochloride
Tetracaine HCl CAS : 136-47-0
Tetracaine HCl Molecular formula: C15H25ClN2O2
Tetracaine HCl Molecular weight: 300.82
Tetracaine HCl EINECS: 205-248-5
Appearance: Fine white crystalline and odorless powder
Melting point: 145~150 degree
Assay: 99%
Grade: Pharmaceutical Grade
Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
Tetracaine HCL Application
Tetracaine HCL chloride is synthesized from 4-butylaminobenzoic acid. The esterification reaction is carried out by acid catalysis to form ethyl ester. The base-catalyzed transesterification is achieved by boiling ethyl 4-butylaminobenzoic acid with an excess of 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine HCL (INN, also known as tetracaine; trade names Pontocaine.Ametop and Dicaine) are potent topical anesthetics of the ester groups. It is mainly used for ophthalmology and antipruritic agents and has been used for spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of the calcium release pathway (Lannottine receptor), which controls the release of calcium in intracellular stores. Dicaine is an allosteric blocker for channel function. At low concentrations, tetracaine causes initial inhibition of spontaneous calcium release events, whereas at high concentrations, tetracaine is completely released.
Tetracaine Hydrochloride Dosage:
1. For tonometry and other short procedures: Instill 1 to 2 drops in the eye(s) just prior to evaluation.
2. For minor surgical procedures, such as foreign body or suture removal: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 1 to 3 instillations.
3. For prolonged anesthesia, such as cataract extraction: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 3 to 5 doses.
Tetracaine HCL Specification
Product Name |
Tetracaine hydrochloride(C15H25ClN2O2) |
CAS: 136-47-0 |
Items Tested |
Specification |
Result |
Characters |
White crystals or a white crystalline powder |
White crystalline powder |
Appearance of solution |
Clear and colourless |
Conform |
Chromatographic purity |
In Pass |
confirm |
Solubility |
Very soluble in water, soluble in Alcohol; |
Comfirm |
Melting range |
145℃~150℃ |
146℃~147.5℃ |
Loss on Drying |
≤ 0.5% |
0.19% |
Residue on ignition |
≤0.10% |
0.05% |
Related substance |
Not more than the reference solution 0.05% |
confirm |
Loss on drying |
≤0.5% |
0.07% |
Heavy metals |
≤10ppm |
confirm |
PH |
4.5-6.5 |
5.8 |
Heavy metals |
≤0.0005% |
Conform |
Sulphated ash |
≤0.1% |
0.05% |
Related substances |
≤0.05% |
Conform |
Assay |
99.0-101.0% |
99.87% |
Storage |
Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation. |
Package
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Local Anesthetic Drugs we supply
Procaine Base |
CAS 59-46-1 |
Lidocaine HCl |
CAS 73-78-9 |
Benzocaine |
CAS 94-09-7 |
Lidocaine Hydrochloride |
CAS 51-05-8 |
Xylocaine Lidocaine |
CAS 137-58-6 |
Tetracaine HCl |
CAS 136-47-0 |
Propitocaine Hydrochloride |
CAS 1786-81-8 |
Aarticaine Hydrochloride |
CAS 23964-57-0 |
Procaine Hydrochloride |
CAS 51-05-8 |
Tetracaine hydrochloride |
CAS 136-47-0 |
Lidocaine Base |
CAS 137-58-6 |
Dyclonine hydrochloride |
CAS 536-43-6 |
Tetracaine Base |
CAS 94-24-6 |
Dibucaine Hydrochloride |
CAS 61-12-1 |
Proparacaine Hydrochloride |
CAS 5875-06-9 |
Ropivacaine Hydrochloride |
CAS 98717-15-8 |
Bupivacaine |
CAS 2180-92-9 |
Bupivacaine Hydrochloride |
CAS 14252-80-3 |