Procaine HCl /Procaine Hydrochloride

Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

Product Details

1.Product Introduction

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Procaine hydrochloride
Product name: Procaine hydrochloride
Synonyms: 2-(Diethylamino)ethyl 4-aminobenzoate; Procaine Hcl; ATOXICAINE; 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride (1:1); 2-methylpropyl 4-aminobenzoate hydrochloride
CAS NO.: 51-05-8
Assay: 99%
Packing: 25kg/drum
M.F.: C13H21ClN2O2
M.W.: 272.771
Appearance: White crystalline powder
Usage: Local anesthetics, used for infiltration anesthesia, nerve block, etc.


procaine hydrochloride was first synthesized by German chemist Albert Einhorn in 1905. He is looking for a compound that can be used as an anesthetic, non-toxic, no side effects, no addiction. Dr. Eindhoven is looking for a compound that can replace cocaine as an anesthetic. Cocaine was used as an anesthetic. However, because cocaine is toxic, addictive, destructive to the central nervous system, its use is illegal. Dr. Einhorn was able to produce a compound that showed the properties he was looking for. This new compound he named as procaine.

“Pro” means replacement, “cocaine” comes from the word cocaine. Because the names are similar, because they are all anesthetized, there is a lot of confusion about the nature of procaine. Sporaine acts as an anesthetic when injected into the muscle, but when taken as a compound in combination, procaine acts as a vitamin. The procaine HCl solution used as an anesthetic was named Norcaine.

Chemical procaine is the PABA ester of amino alcohol DEAE. PABA (p-aminobenzoic acid) is a “B” vitamin. DEAE, (n, n diethylaminoethanol) is a biologically active precursor of & quot; B & quot; vitamin choline. (Figure 1) procaine is usually used in the form of hydrochloride (procaine HCl) because it is highly water soluble. Oral administration of procaine hydrochloride is mainly absorbed through the small intestine villi into the body. Experiments show that most of the procaine HCl enters the blood completely through the molecular formula. In the blood, procaine HCl is rapidly hydrolyzed into the PABA and DEAE by the enzyme, which is the two components of the procaine molecule. These metabolites are removed by the liver, chemically changed, and excreted in the urine.

4.prodection details

Product name

Procaine hcl

Other name

Procaine hydrochloride, aminocaine;anadolor;atoxicocaine;

CAS register number




Molecular formula


Molecular weight





White crystalline powder


1kg/aluminium foil bag or as required


can be used as pharmaceutical material

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