Procaine HCl Procaine Hydrochloride CAS 51-05-8 for Pain Relieve
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Keywords: Procaine HCL, Procaine hydrochloride, Naucaine, Procaine HCI, CAS 51-05-8
1. Product Introduction
Data of Procaine HCL Powder
Procaine HCL Product Name: Procaine hydrochloride;
Procaine HCL Alias: Procaine HCL, Procaine, Naucaine
Procaine HCL CAS: 51-05-8
Procaine HCL MF: C13H21ClN2O2
Procaine HCL MW: 272.77
Procaine HCL EINECS: 200-077-2
Procaine HCL Appearance: white crystalline powder
Procaine HCL Usage: local anesthetic used as a pharmaceutical intermediate for infiltration anesthesia, nerve block
2. Product description:
Procaine hydrochloride is a local anesthetic that can temporarily block the conduction of nerve fibers and has a narcotic effect, the role of strong, low toxicity, and no addiction, but the skin, mucous membranes penetrate weak, suitable for surface anesthesia, patients are used for infiltration, spine and conduction anesthesia.
3. Procaine HCL COA:
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Product name |
Procaine Hydrochloride |
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CAS No. |
51-05-8 |
Outer Packing |
25KG/drum |
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Production date |
2018.08.25 |
Shelf life |
2021.08.24 |
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Standard adopted |
USP37 |
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Items of analysis |
Specification |
Results |
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Description |
A white crystalline powder or colourless crystals |
Complies |
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Identification |
IR Absorption |
Complies |
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Melting point |
153-158℃ |
156.2-157.6℃ |
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Color of solution |
Colorless and clear |
Conforms |
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Heavy metals |
≤0.002% |
<0.002% |
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PH (Acidity) |
5.0~6.5 (≤0.02NNaOH0.5ml) |
5.5/0.2ml |
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Chromatographic purity |
≤0.05%(Sum≤1.0%) |
Conforms |
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Loss on drying |
≤0.5% |
0.16% |
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Sulphated ash |
≤0.1% |
0.05% |
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Assay |
99.0~101.0% |
99.8% |
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Bacterial endotoxins |
≤0.6EU/mg |
<0.6EU/mg |
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Conclusion |
Qualified |
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4. Product Application:
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain. Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.
5. Related Products:
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Local Anesthetic powder |
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Articaine |
23964-58-1 |
Mepivacaine |
22801-44-1 |
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Articaine HCL |
23964-57-0 |
Mepivacaine HCL |
1722-62-9 |
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Benzocaine |
94-09-7 |
Pramoxine HCL |
637-58-1 |
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Bupivacaine |
2180-92-9 |
Prilocaine |
721-50-6 |
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Bupivacaine HCL |
14252-80-3 |
Prilocaine HCL |
1786-81-8 |
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Cinchocaine |
85-79-0 |
Procainamide HCL |
614-39-1 |
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Dibucaine HCL |
61-12-1 |
Procaine |
59-46-1 |
|
Proparacaine HCL |
5875-06-9 |
Procaine HCL |
51-05-8 |
|
Levobupivacaine |
27262-47-1 |
Ropivacaine HCL |
98717-15-8 |
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Levobupivacaine HCL |
27262-48-2 |
Ropivacaine Mesylate |
854056-07-8 |
|
Lidocaine |
137-58-6 |
Tetracaine |
94-24-6 |
|
Lidocaine HCL |
6108-05-0 |
Tetracaine HCL |
136-47-0 |
|
Trimecaine |
616-68-2 |
TriMecaine HCl |
1027-14-1 |
6. Order Process:
-Know what would you need
-Send you total price and make shipping plan
-If you think ok and send payment
-We will ship the parcel in 12-24 hours and then send packing photo and tracking number to you
-We will keep tracking it and let you know the details
-Parcel will be delivered in 4-5 working days
7. The quality control process:
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
