Procaine HCL CAS.51-05-8

Procaine hydrochloride is a local anesthetic that can temporarily block the conduction of nerve fibers and has a narcotic effect, the role of strong, low toxicity, and no addiction, but the skin, mucous membranes penetrate weak, suitable for surface anesthesia, patients are used for infiltration, spine and conduction anesthesia.

Product Details

Procaine HCl Procaine Hydrochloride CAS 51-05-8 for Pain Relieve

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Keywords: Procaine HCL, Procaine hydrochloride, Naucaine, Procaine HCI, CAS 51-05-8


1. Product Introduction

Data of Procaine HCL Powder

Procaine HCL Product Name: Procaine hydrochloride;

Procaine HCL Alias: Procaine HCL, Procaine, Naucaine

Procaine HCL CAS: 51-05-8

Procaine HCL MF: C13H21ClN2O2

Procaine HCL MW: 272.77

Procaine HCL EINECS: 200-077-2

Procaine HCL Appearance: white crystalline powder

Procaine HCL Usage: local anesthetic used as a pharmaceutical intermediate for infiltration anesthesia, nerve block


2. Product description:

Procaine hydrochloride is a local anesthetic that can temporarily block the conduction of nerve fibers and has a narcotic effect, the role of strong, low toxicity, and no addiction, but the skin, mucous membranes penetrate weak, suitable for surface anesthesia, patients are used for infiltration, spine and conduction anesthesia.


Procaine HCL (4)


3. Procaine HCL COA:

Product name

Procaine Hydrochloride

CAS No.

51-05-8

Outer Packing

25KG/drum

Production date

2018.08.25

Shelf life

2021.08.24

Standard adopted

USP37

Items of analysis

Specification

Results

Description

A white crystalline powder or colourless crystals

Complies

Identification

IR Absorption
Reaction of chlorides
Reaction of primary aromatic amines

Complies

Melting point

153-158℃

156.2-157.6℃

Color of solution

Colorless and clear

Conforms

Heavy metals

≤0.002%

<0.002%

PH (Acidity)

5.0~6.5 (≤0.02NNaOH0.5ml)

5.5/0.2ml

Chromatographic purity

≤0.05%(Sum≤1.0%)

Conforms

Loss on drying

≤0.5%

0.16%

Sulphated ash

≤0.1%

0.05%

Assay

99.0~101.0%

99.8%

Bacterial endotoxins

≤0.6EU/mg

<0.6EU/mg

Conclusion

Qualified


4. Product Application:

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.


Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.


Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain. Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.


Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.


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6. Order Process:

-Know what would you need

-Send you total price and make shipping plan

-If you think ok and send payment

-We will ship the parcel in 12-24 hours and then send packing photo and tracking number to you

-We will keep tracking it and let you know the details

-Parcel will be delivered in 4-5 working days


7. The quality control process:

1)Purchasing

Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.

2) Inspection

Four steps: sampling, sample pretreatment, measuring and data processing.

3) Producing

a)Each operator must do self-inspection of products and make the corresponding inspection records.

b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.

4) Before selling

Test result can be provided before selling.

Third-party detection institution is allowed if you are not satisfied with test results.

Procaine HCL (5)

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