Pain killer Lidocaine Powder
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Keywords: Lidocaine, Xylocaine
1. Product Introduction
Product Name: Linocaine Base
2. Product description:
Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated.
Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.3. Lidocaine COA:
| Items Tested | Specification | Result |
| Characters | White crystal powder with characteristic odor | White crystal powder with weak odor |
| Melting point | Melting point: 66 degree to 70 degree | 66.6 degree-68.5 degree |
| Identification | BCDE Comply with the requirement | Conforms |
| Appearance of solution | Clear and colorless | Conforms |
| Water | Not more than 0.5% | 0.3% |
| Sulphate | Not more than0. 1% | Conforms |
| Chloride | Not more than 0. 0035% | 0.0025% |
| Heavy Metals | Not more than 0.002% | 0.001% |
| Residue on Ignition | Not more than 0.1% | 0.02% |
| Impurity (26-dimethylaniline content) | Not more than 0.01% | Conforms |
| Assay (HPLC) | 99.0%-101.0% | 99.6% |
| Conclusion | Conforms BP2007 | |
4. Lidocaine Application:
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such asbupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action. For surface anesthesia, several available formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful.Lidocaine drops can be used on the eyes for short ophthalmic procedures.
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