Pain killer Lidocaine HCl Powder
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Keywords: Lidocaine, Xylocaine, lidocaine hydrochloride
1. Product Introduction
Product Name: lidocaine hydrochloride
Alias:lidocaine hcl
CAS No.: 73-78-9
EINECS No.: 200-803-8
Molecular Formula: C14H23ClN2O
Molecular Weight: 270.8
Melting point: 80-82°C
Appearance: white crystalline powder
Standard: Enterprise Standard
Packing: 25KG/Drum or as per your requirements
Application: local anesthetic;anti-arrhythmia agent
2. Product description:
Lidocaine Hcl, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine (aka adrenaline) vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e.g. for endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.
3. Lidocaine HCl COA:
| Product name | Lidocaine HCL | ||
| CAS No. | 6108-05-0 | Outer Packing | 25KG |
| Production date | 2018-07-22 | Shelf life | 2020-07-21 |
| Standard adopted | EP8.5 | ||
| Items of analysis | Specification | Results | |
| Appearance | White crystalline powder | White crystalline powder | |
| PH | 4.64 | 4.5-5.5 | |
| Residue on ignition | ≤0.1% | 0.05% | |
| Moisture | 5.0%-7.0% | 6.43% | |
| Heavy metals | <5ppm | ≤5ppm | |
| Solvent Residue | Methanol ≤0.5% Toluene ≤0.089 | 0.068% 0.002% | |
| Related substance | Impurity A≤0.01% Unknown Impurity≤0.1% | Not detected 0.01% | |
| Assay | 97.5%-101.0% | 99.86% | |
| Conclusion | Qualified | ||
4. Lidocaine HCl Application:
Lidocaine Hydrochloride contains the active ingredient lidocaine hydrochloride (previously known as lignocaine hydrochloride ).Lidocaine is a type of medicine called a local anaesthetic. It is used to numb areas that would otherwise feel pain.Pain is caused by the stimulation of pain receptors at the ends of nerves. The stimulation causes sodium to enter the nerve ending, which causes an
electrical signal to build up in the nerve. When this electrical signal is big enough, it passes along the nerve to the brain, where the signal is interpreted as pain.
Lidocaine HCL works by temporarily blocking this pathway of pain signals along nerves. It does this by stopping the sodium entering the nerve ending at the site of the pain. This prevents an electrical signal building up and passing along the nerve fibres to the brain.Lidocaine injection is also used in the emergency treatment of heart rhythm disturbances, particularly in cases of suspected or proven heart attack. It is given by intravenous infusion or intravenous bolus injection.
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