Local Anesthetic Agent Articaine HCL CAS 23964-57-0
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Articaine Hydrochloride Basic Info
| Product Name | Articaine hydrochloride |
| Alias | Articaine HCL |
| CAS | 23964-57-0 |
| MF | C13H20N2O3S.HCl |
| MW | 320.84 |
| EINECS | 245-957-7 |
| Assay | 99.0% |
| PHYSICAL STATE | White Crystalline Powder |
| Solubility | Very soluble in alcohol and in acetone; slightly soluble in water. |
| Usage | Local Anesthetic Agents |
| Storage | keep in cool, dry place |
| Package methods | hundreds of disgusied pacakges |
| After-sales service | Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible. |
| Shipping method | FedEx,UPS,DHL,EMS, Fedex and so on, by air or sea.Will choose the best shipping way. |
| Delivery time | delivery quickly at the day when receive the payment, will be deliveried in 4-7days after tracking |
| Payment Methods | Western union, money gram, bitcoin and bank transfer |
Articaine hydrochloride Descrption
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. Articaine is prolonged by combining the drug with a vasoconstrictor such as adrenaline. Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand , food surgery and in dentistry.
The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
Articaine hydrochloride Application
Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient
and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.
Articaine is a dental amide-type local anesthetic.Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia.In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine works well.
Articaine blocks nerve conduction by reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, similar to other local anesthetics. Binding of articaine to the sodium channel reduces sodium influx so that the threshold potential will not be reached and impulse conduction stops. The blocking action of articaine on the sodium channel is state dependent: it has the highest affinity for the open state, an intermediate affinity for the inactivated state, and the lowest affinity for the resting state.
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