Raw peptides ACE 031 for muscle building with safe delivery
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Product name: ACE 031 (85%)
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ACE-031 is an investigational protein therapeutic that builds muscle and increases strength by inhibiting molecules that bind to and signal through a cell surface receptor called Activin Receptor Type IIB (ActRIIB).
ACE-031 is a recombinant fusion protein that is produced by joining a portion of the human ActRIIB receptor to a portion of a human antibody.
ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption,diagnostic, therapeutic procedures, agricultural and veterinary purposes.ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.
ACE 031 Application:
In nature, this effect has been observed in numerous species, particularly in animals that have been bred for increased musculature and strength. For example, Belgian Blue cattle lack the gene for GDF-8, which is one of several molecules that activate the ActRIIB receptor. A deficiency of this protein results in cattle with tremendously developed musculature and strength. Similar effects have been observed in other species, including rodents, dogs and even humans.
Treatment with ACE-031 promotes muscle growth by inhibiting ActRIIB signaling. ACE-031 binds to proteins that signal through the ActRIIB receptor to limit muscle growth. When ACE-031 binds to these proteins, it prevents them from interacting with the ActRIIB receptor, thus allowing muscle to grow. Moreover, because ACE-031 prevents GDF-8 and other proteins that regulate muscle mass from signaling through the ActRIIB receptor, its effects on lean muscle exceed those of inhibitors of GDF-8 (myostatin) alone.
Sportsmen taking 1 mg of ACE-031 once a week over the period of 3-4 weeks report nearly an immediate increase in the muscle hardness and the rapid growth of muscle mass and strength to an extent exceeding even the most efficient hardcore volume anabolic-androgenic steroid!
Another dosing option is to start with the dose of 200 mcg of ACE-031 per day and to increase the dose every week by 100 mcg, whereas the treatment cycle should last again 3-4 weeks.
Once a cycle with ACE-031 is completed, a break in the duration of two weeks is recommended.
During the studies done on Ace-031, where rats were injected, they were given 10mg/kg. Hence, to match those types of figures, a normal sized adult bodybuilder would have to use about 1 gram a month, all things being equal. This means that if you were to use a gram it would cost you tens of thousands of dollars to get in that amount each month.
1. Fat loss and bone health
In the different studies conducted, the subjects experienced a decrease in leptin concentration and promoted adiponectin, which was a "good fat" hormone. So maybe Ace-031 does help to lose weight. Another study shows that the increase in alkaline phosphatase in blood and the reduction of collagen peptides; this may mean that it also helps to strengthen the bones.
2. Women weight loss
For overweight women were given a dose of 250 mg (mg) Ace 031. As a result, after one month, thigh muscle grew more than a pound. In addition, their lean weight increased by 3%, which is quite a result.
In the study with women, the concentration of FSH (follicle-stimulating hormone) decreased significantly and did not explain why. So there seems to be some side effects, we do not know whether men will happen the same thing. But we know that in the cattle, due to infertility, farmers refused to use Ace-031 "to strengthen" their stock.
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