Lyophilized Peptide Dermorphin

Dermorphin is a peptide expressed by the frog venom skin glands with a potent opiate-like activity on mu-type opioid receptors, which have potent depressive and analgesic effects. Any needs contact :whatsapp:+8613378646535 Emails:eleven11@chembj.com

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                    Raw peptide Dermorphin for muscle building with safe delivery 


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Dermorphin

Basic Information: 

CAS No: 77614-16-5 

Synonyms: H-TYR-D-ALA-PHE-GLY-TYR-PRO-LYS-NH2; (Lys7)-Dermorphin

Molecular Formula: C40H50N8O10

Molecular Weight: 802.89

Form: Dermorphin Peptide Hormone ready in 10mg/vial. a strong analgesic. 

Packing: 10mg / vial or 100mg/tube

MOQ: 5-10vials


Dermorphin Application:


Dermorphin is a hepta-peptide first isolated from the skin of South American frogs belonging to the genus Phyllomedusa. The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors.


Dermorphin is about 30-40 times more potent than mor-phine but theoretically may be less likely to produce drug tolerance and addiction (due to its high potency). The amino acid sequence of dermorphin is H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2.


Dermorphin is not found in humans or other mammals and similar D-amino acid peptides have only been found in bacteria, amphibians and molluscs. Dermorphin appears to be made in these through an unusual posttranslational modification carried out by an amino acid isomerase. This unusual process is needed because the D-alanine in this peptide is not among the 20 amino acids coded for in the genetic code and thus the peptide cannot be synthesized in the usual way from the encodings in the genome of an organism.


Dermorphin has been illegally used in horse racing as a performance-enhancing drug. Due to dermorphin's painkilling activity, horses treated with dermorphin may run harder than they would otherwise

Dermorphin

More about Dermorphin:


The fact that a substance is described as being 30-40 times more potent than morphinee does not mean that it is more effective than morphine in abolishing pain. It means that it can abolish the pain at a lower dose.


Research on Dermorphin


"Dermorphin is a substance that has been demonstrated to act as an agonist at the mu-opiate receptor," Sams says. "Other mu-opiate agonists are morphinee, fentany, and etorphinee.


We typically associate these substances with analgesic effects in people and dogs, but they produce a paradoxical effect in horses that results in increased locomotor activity at low doses and low blood concentrations."


Dermorphin Storage:


Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.

Dermorphin raws

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