Hexarelin is a synthetic GH secretagogue, structurally similar to GHRP-6, which is in the growth factor family known as Growth Hormone Releasing Peptides or GHRPs. The results of several studies conducted on both mice and rats has led to the conclusion that Hexarelin is one of the most powerful GH-Releasing Peptides. Hexarelin, unlike GHRP-6, does not increase appetite because of its inability to drastically increase Ghrelin levels, which is responsible for the increased appetite and quicker gastric emptying. Hexarelin is a synthetic growth hormone secretagogue made from six amino acids.
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Product Name: Hexarelin
Other Name: Hexarelin Acetate CAS: 140703-51-1 Sequence: His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH2 MF: C47H58N12O6 MW: 887.04 Purity (HPLC): 99.00% Single Impurity (HPLC): 0.5%max Amino Acid Composition: ±10% of theoretical Peptide Content (N%): ≥80.0% Water Content(Karl Fischer): ≤8.0% Acetate Content(HPIC): ≤10.0% Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc) MS(ESI): Consistent Mass Balance: 95.0~105.0% Appearance: White powder Usage: Pharmaceutical intermediates. Packing: 2mg/vial, 5mg/vial, 10vials/kit
Hexarelin has a peptide purity level that exceeds 99.0% as determined by HPLC. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.
Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the factor family which stimulates the release of growth hormone (GH). Hexarelin can be used medically to treat GH deficiency. Hexarelin is becoming a popular choice as a performance enhancement drug.
Due to Hexarelin's ability to increase secretion of natural Hormone, most of its effects are similar to those of synthetic GH, although to a slightly lesser extent.
How does it Work?
When Hexarelin is given as a subcutaneous injection, it activates the pituitary via a pulse, just like GHRP-6, and helps circulate growth hormone in the body. Unlike GHRP-6, it does not induce any hunger side effects. Hexarelin has the ability to not only raise the level of GH in the body but to also suppress somatostatin, which is the main culprit that inhibits GH from being released. This means that there will be more GH in abundance. In addition, hexarelin is the strongest GHRP available, so users should notice that desensitization can come much quicker than other GHRP’s. This makes it less ideal for long term use, but with hexarelin’s ability to raise healthy levels of IGF-1 and GH it can work perfect as a PCT tool for those coming off a synthetic GH/IGF-1 cycle. The potency of this peptide should not be underestimated and it comes with an increase in cortisol production as well as prolactin. Nothing close to what might be seen in elevated levels from steroid use, but compared to other GHRP’s it has the strongest affinity to raise cortisol/prolactin.
Dosage and Usage
Hexarelin comes in a freeze dried powder just like the other GHRP peptides and storage should be done in a cool dry place until reconstituted and placed in a refrigerator. Bacteriostatic water is used to reconstitute the powder and an insulin syringe is the preferred method for administering subcutaneous injections of hexarelin. Users will notice 200mcgs is the saturation dose for hexarelin and over a few weeks of use total desensitization may begin to take place. Also, the occasional flare up of the pituitary has been noted when dosing far beyond saturation doses. Desensitization can be cleared easily by taking a break from hexerlin usage for a few days to a few weeks. This GHRP is the strongest, and because of the desensitization factor, I believe the optimal way to use this peptide would be to blend it at low doses with other GHRP’s like GHRP2, GHRP6 or iPamorelin. By combining a low dose of hexearelin with another GHRP, you are going to increase your ability to put out a greater pulse of growth hormone. Combine this with GHRH’s and you have a synergistic blend that will release GH more effectively. In fact, for synthetic HGH users, this may be a viable way to save money on using less exogenous GH by combining it with hexarelin in a GHRP+GHRH cycle. As a result, utilizing hexarelin in this protocol would establish the maximum GH release in the body.
Solubility & Storage:
It is recommended to reconstitute the lyophilized Hexarelin in sterile water, which can then be further diluted in other aqueous solutions. Lyophilized Hexarelin although stable at room temperature for 3-4 weeks, should be stored desiccated below -18°C. Upon reconstitution, Hexarelin should be stored at 4°C out of direct light for between 10-14 days and for future use below -18°C. Prevent repeated freeze-thaw cycles.
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