Azelaic Acid Anti-Allergic Agents

Azelaic Acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne. It belongs to a class of medication called dicarboxylic acids. It works by killing acne bacteria that infect skin pores.

Product Details


1.Product Introduction

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2.Specifications:


Product Name: Azelaic Acid
Synonym: Nonanedioic acid
Molecular Formula: C9H16O4
Molecular Weight188.22

EINECS No: 204-669-1
CAS NO. : 123-99-9
Solubility: Slightly soluble in cold water, soluble in water, ether, soluble inethanol
Assay: 99.5%
Appearance: white crystal powder




3.Applications:

For alkyd resins, paints and chemical synthesis. Most of azelaic acid for the production of azelaic acid dimethyl octyl (DOZ) plasticizers, other uses as spices, oil, oil, polyamide resin material. DOZ also be used as synthetic rubber softener. Ammonia azelaic acid through dehydration, can be prepared from azelaic dinitriles.

 

 

1.External to the skin on a variety of aerobic and anaerobic bacteria with inhibitory and killing effects, topical 20% azelaic acid cream can significantly reduce the skin bacteria Propionibacterium acnes within the follicle class and the growth of bacteria and skin surface lipid free fatty acid content decreased. High antibacterial activity, rapidly enter the cell, caused by a variety of different causes skin has a good antibacterial effect.

 

 

2.The normal skin and acne skin infection effects of anti horny, its mechanism is to reduce the follicular hyperkeratosis.

 

 

3.Anti-proliferative and anti-cytotoxic effect, it is through the destruction of mitochondrial respiration and cell DNA synthesis, rather than inhibit the activity of tyrosinase.



4.prodection details


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Physical Properties

Index

PURITY, (wt.%), min

99.0

Physical state

white crystalline powder

Acid Value

587~594

Melting point (°C)

 102~109 

Boiling point  (°C)

286 

Flash point (°C)

215 

Specific gravity,g/cm3

 1.225 

Arsenic (% ),max 

0.0005 

Iron (Fe),Max,PPM  

0.003

Single-acid content (%).max

0.09

Heavy metal, max  PPM

5


EP-Standard-Cosmetic-Grade-Azelaic acid


5. Packaging & Delivery
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1. Packing: 1kg with double plastic container inside/Aluminum foil bag outside;25kg with double plastic container inside/Fiber drum outside.
2. Storage: Stored in a cool & dry well-closed container, keep away from moisture and strong light/heat.
3. Shelf life: Two years under well storage situation.


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