Avanafil is a selective inhibitor of phosphodiesterase type 5 (PDE5). It relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Avanafil is used to treat erectile dysfunction (impotence).
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Product Name:Avanafil Synonyms:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide CAS:330784-47-9 MF: C23H26ClN7O3 MW:483.95 Chemical Properties:White or off-white crystalline power MP:150-152°C Usage:Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM. Packing:As required
In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfil treatment compared to the placebo group.
Erections were improved in 72% of the Viagra group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.
COA of Avanafil:
White or off-white crystalline power
Practically insoluble in water and Slightly soluble in ethanol
Loss on drying
Any other impurities
5. Packaging & Delivery
we have adequate stock,and can arranged within 24 hours when receive the payment.tracking number would be informed quickly after shipment.
we have special way could ship 2kg to 20tons products a time. we offer melting powder into liquid service .and ship the liquid in special bottles.
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